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| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC12333 | ML-109 Featured | ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM. |
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| DC7781 | ML-224 Featured | ML-224 (ANTAG3) is a selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice. |
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| DC28610 | TSHR antagonist S37a | TSHR antagonist S37a is a highly selective thyrotropin receptor (TSHR) antagonist, with potential for the treatment of Graves' orbitopathy. |
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| DC28611 | TSHR antagonist S37 | TSHR antagonist S37 is a selective and competitive thyrotropin receptor (TSHR) antagonist. TSHR antagonist S37 is the racemate of TSHR antagonist S37a. |
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| DC28999 | NCGC00229600 | NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves' disease. |
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| DC40415 | TSHR antagonist S37b | TSHR antagonist S37b is an enantiomer of TSHR antagonist S37a, shows only a minor effect for TSHR inhibition. TSHR antagonist S37b can be used for the research of thyroid function. |
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| DC73510 | Org 274179-0 Featured | Org 274179-0 is a highly potent, allosteric antagonist of the thyroid-stimulating hormone receptor (TSH receptor), inhibits bTSH-, hTSH- and M22-mediated CRE-luciferase transactivation in the CHO cell line. |
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| DC73511 | SYD5115 (SYD-5115, SYD 5115) | SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively. |
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