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Parkinson Disease

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Cat. No. Product Name Field of Application Chemical Structure
DC11523 Landipirdine A novel 5-HT receptor antagonist for the treatment of Parkinson's disease..
DC11895 Foliglurax hydrochloride A potent, selective, brain-penetrant and orally bioavailable mGluR4 positive allosteric modulator with EC50 of 79 nM.
DC11894 Foliglurax A potent, selective, brain-penetrant and orally bioavailable mGluR4 positive allosteric modulator with EC50 of 79 nM.
DC8883 BP897 Featured BP897 is a partially selective D3 dopamine receptor agonist.
DC11103 Tavapadon Featured Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors.
DC7014 GPI-1046 For the detailed information of GPI-1046, the solubility of GPI-1046 in water, the solubility of GPI-1046 in DMSO, the solubility of GPI-1046 in PBS buffer, the animal experiment (test) of GPI-1046, the cell expriment (test) of GPI-1046, the in vivo, in vitro and clinical trial test of GPI-1046, the EC50, IC50,and Affinity of GPI-1046, Please contact DC Chemicals..
DC7419 GNE-7915 Featured GNE-7915 is a highly potent, selective, and brain-penetrable LRRK2 small molecule inhibitor with IC50 of 9 nM in cellular LRRK2 assay; > 100 fold selectivity against a panel of 187 kianses(Ki).
DC8379 JH-II-127 Featured JH-II-127 is a highly potent, selective, and brain penetrant LRRK2 inhibitor.
DC8970 Pramipexole Base Pramipexole is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS).
DC3151 Pramipexole dihydrochloride Pramipexole is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.
DC5015 Rotigotine Hydrochloride Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity.
DC4134 Safinamide Safinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A.
DC11485 Tolcapone Featured Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor.
DC9332 Tozadenant Tozadenant (SYN-115) is an adenosine A2A receptor antagonist.

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