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Cat. No. Product name CAS No.
DC11868 Freselestat

A potent, selective and orally active human neutrophil elastase (HNE) inhibitor with Ki of 12 nM.

DC10417 Acumapimod (BCT197) Featured

Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α.

DC11723 AZD-7986(Brensocatib) Featured

AZD-7986(Brensocatib) is a highly potent, reversible, and selective DPP1 inhibitor with enzyme and cell pIC50 of 8.4.

DC10021 Batefenterol Featured

Batefenterol(GSK961081,TD-5959)is a Muscarinic Antagonist and β2-Agonist possessing both muscarinic antagonist (MA) and β2-adrenoceptor agonist (BA) properties (MABA).

DC11859 BAY85-8501

BAY 85-8501 (BAY85-8501) is a potent, selective human neutrophil elastase (HNE) inhibitor with IC50 of 65 pM.

DC9582 Cilomilast

Cilomilast(SB 207499; Ariflo) is a potent PDE4 inhibitor with IC50 of about 110 nM, has anti-inflammatory activity and low central nervous system activity.

DC9689 Danirixin (GSK1325756) Featured

Danirixin(GSK1325756) is a selective CXCR2 antagonist.

DC8779 Glycopyrrolate Featured

Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.

DC9943 PI3Kδ inhibitor GS2269557

GSK-2269557 is a potent and selective PI3Kδ inhibitor over the closely related isoforms.

DC9944 PI3Kδ inhibitor GS2292767

GSK2292767 is a potent and selective PI3Kδ inhibitor.

DC8767 GSK256066 Featured

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.

DC10384 Olodaterol Featured

Olodaterol (BI1744) is a long acting β2-adrenoceptor agonist with an EC50 of 1.4±0.08 nM.

DC9248 Olodaterol(BI-1744) hydrochloride Featured

Olodaterol is a novel, long-acting beta2-adrenergic agonist (LABA) that exerts its pharmacological effect by binding and activating beta2-adrenergic receptors located primarily in the lungs.

DC9410 SCH 527123

SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.

DC8813 TD-4208 Featured

TD-4208 is a potent and selective inhaled muscarinic antagonist with functional lung selectivity and long duration of action in preclinical models of bronchoconstriction.

DC7516 TG100-115 Featured

TG100115 is a PI3Kγ/δ inhibitor with IC50 of 83 nM/235 nM, with little effect on PI3Kα/β. Phase 1/2.

DCAPI1449 Tiotropium Bromide Featured

Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation.

DC8153 Umeclidinium bromide Featured

Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD).

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