Cat. No. | Product name | CAS No. |
DC11622 |
MAP3K14-IN-173
A novel potent MAP3K14 kinase inhibitor with IC50 of 1.8 nM (NIK autophosphorylation). |
2113617-02-8 |
DC11610 |
AKS1-IN-19
A novel potent, selective and orally active ASK1 (MAP3K5) inhibitor with pIC50 of 8.3. |
2089638-10-6 |
DC11558 |
DLK-IN-14
A potent, selective, CNS penetrant dual leucine zipper kinase (DLK, MAP3K12) inhibitor with Ki of 3 nM. |
1620574-24-4 |
DC10781 |
ASK1-IN-1
Featured
ASK1-IN-1 is an apoptosis signal regulating kinase 1 (ASK1) inhibitor extracted from patent WO2016025474A1, Compound 4. |
1262041-49-5 |
DC9555 |
Cot inhibitor-2
Cot inhibitor-2 is a COT/Tpl2 inhibitor. |
915363-56-3 |
DC10106 |
GNE-3511
Featured
GNE-3511 is a potent and selective zipper kinase (DLK, MAP3K12) inhibitors. |
1496581-76-0 |
DC8787 |
NQDI-1
Featured
NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. |
175026-96-7 |
DC11036 |
TCASK10
TCASK10 is a potent, highly specific inhibitor of ASK1 with IC50 of 14 nM, 30-fold selectivity over ASK2 (IC50=510 nM) and no activity against MEKK1, TAK1, IKKβ, ERK1, JNK1, p38α, GSK-3β, PKCθ and B-raf. |
1005775-56-3 |
DC9873 |
Selonsertib(GS-4997)
Featured
Selonsertib(GS-4997)is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. |
1448428-04-3 |