Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Fumarase
Cat. No. Product name CAS No.
DC70121 Fumarase-IN-2 sodium

A cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle); elicits a nutrient-dependent cytotoxicity in a number of cancer cell lines, and displays increased growth-inhibitory activity toward SW620 cell line grown in the absence of glucose (mean IC50=2.2 uM).

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