Home > Inhibitors & Agonists > Tyrosine Kinase > Ephrin Receptor
Cat. No. Product name CAS No.
DC10209 ALW-II-41-27 Featured

ALW-II-41-27 is a novel Eph receptor tyrosine kinase inhibitor, used for cancer treatment.

DC7473 NVP-BHG712 Featured

NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.

DC11073 UniPR1331

UniPR1331 (UniPR-1331) is a selective, orally available antagonist of Eph/ephrin interaction with pIC50 of 5.45, IC50 of 2.9 uM.

DC50113 UniPR129

UniPR129 is a potent but problematic Eph/ephrin antagonist. UniPR129 has the potential for the research of cancer disease.

DC72101 BT5528

BT5528 is a bicyclic peptide toxin conjugate, an EphA2 activator. BT5528 is made up of a bicyclic peptide and Auristatin E, is derivated from BCY6099. BT5528 shows potent anti-tumor activity without bleeding or coagulation toxicity in rats model.

DC74405 Targefrin

Targefrin is a potent, selective antagonist targeting ligand binding domain of receptor tyrosine kinase EphA2 (EphA2-LBD), binds to EphA2-LBD with Kd of 21 nM (ITC) and shows IC50 value of 10.8 nM in biochemical assays.

DC74406 WCDD301

WCDD301 is a high-affinity, orally available agonist of EphA4 receptor.

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