Cat. No. | Product name | CAS No. |
DC11809 |
APX-115
Featured
APX-115 (Ewha 18278) is a first-in-class, orally active, pan-NADPH oxidase (Nox) inhibitor with Ki of 1.08, 0.57, 0.63 nM for Nox1, Nox2, and Nox4, respectively. |
1270084-92-8 |
DC8118 |
GKT137831(Setanaxib)
Featured
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 140±40 nM and 110±30 nM; a potent inhibitor of fibrosis and hepatocyte apoptosis. |
1218942-37-0 |
DC11009 |
GLX351322
Featured
GLX351322 is an inhibitor of NADPH oxidase 4, and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μ M. |
835598-94-2 |
DC10841 |
VAS 2870
Featured
VAS2870 is a selective inhibitor of the NADPH oxidases. |
722456-31-7 |
DC28531 |
Fulvene-5
Fulvene-5 is a potent NADPH oxidase 4 (NOX4) inhibitor with antioxidant properties. Fulvene-5 is a reactive oxygen species (ROS) modifying agent and a potent radioprotector. Fulvene-5 has antitumor activity. |
1075723-01-1 |
DC40030 |
GKT136901
GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 also is a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity. |
955272-06-7 |