Home > Research Areas > Neurological Disease > Spinal Muscular Atrophy (SMA)
Cat. No. Product name CAS No.
DC11674 PF-DcpSi

A potent inhibitor of the mRNA decapping scavenger enzyme (DcpS) with IC50 of 0.11 nM.

DC11673 CK-2127107 Featured

CK-2127107(CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM.

DC10892 LMI070 (NVS-SM1) Featured

LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.

DC10191 RG7800

RG7800 a small molecule SMN2 splicing modifier to enter human clinical trials to treat spinal muscular atrophy.

DC9538 TRO 19622 Featured

TRO19622, a small cholesterol-like molecule, is a neuroregenerative and neuroprotective compound.

DC12267 Verdiperstat (AZD3241) Featured

Verdiperstat is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders.

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