Home > Inhibitors & Agonists > Cytoskeleton/Cell Adhesion Molecules > Microtubule/Tubulin
Cat. No. Product name CAS No.
DCS-091 Cephalomannine

>98%,Standard References

DCC-002 Vinblastine

>98%,Standard References

DCQ-004 4'-Demethylepipodophyllotoxin

>98%,Standard References

DC11928 MPT0B002

A novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells.

DC11935 PBOX-15

A novel microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells.

DC11694 STK899704

A novel tubulin inhibitor that inhibits the proliferation of cancer cell lines with IC50 of 0.2-1.0 uM.

DC7353 ABT-751(E 7010) Featured

ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively.

DC4186 Cabazitaxel

Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid.

DC11107 CKD-516

CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo.

DC5134 lexibulin (CYT997)

CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2.

DC10953 DZ-2384

DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types.

DC4198 Epothilone B Featured

Epothilone B is a Taxol-like microtubule-stabilizing agent with EC0.01 of 1.8 μM.

DCAPI1539 Eribulin Mesylate

Eribulin Mesylate

DCAPI1516 Eribulin

Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules.

DC5882 Fosbretabulin disodium Featured

Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis.

DCAPI1510 Ixabepilone Featured

Ixabepilone (Azaepothilone B; BMS 247550) is an epothilone B analog and nontaxane microtubule-stabilizing compound with clinical activity in a range of solid tumors.

DC11241 MP-HJ-1b

MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation.

DC7023 Ombrabulin Featured

Ombrabulin (AVE8062) hydrochloride is a synthetic derivative of CA-4-P, which inhibits growth in a large number of drug-resistant animal tumors and carcinogen-induced tumors.

DC10981 Plocabulin

Plocabulin (PM060184) is a novel tubulin-binding agent binding to αβ-tubulin dimer with nanomolar affinity, inhibits a panel of 23 tumor cell lines with GI50 of 20 pM-5 nM.

DC11225 VERU-111

VERU-111 (VERU111) is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities.

DC11227 VERU-111 analogue 13f

VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities.

DC4184 Vinorelbine Ditartrate Featured

Vinorelbine (Navelbine) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

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