Cat. No. | Product name | CAS No. |
DCS-091 |
Cephalomannine
>98%,Standard References |
71610-00-9 |
DCC-002 |
Vinblastine
>98%,Standard References |
865-21-4 |
DCQ-004 |
4'-Demethylepipodophyllotoxin
>98%,Standard References |
6559-91-7 |
DC11928 |
MPT0B002
A novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. |
946077-08-3 |
DC11935 |
PBOX-15
A novel microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells. |
354759-10-7 |
DC11694 |
STK899704
A novel tubulin inhibitor that inhibits the proliferation of cancer cell lines with IC50 of 0.2-1.0 uM. |
1578247-29-6 |
DC7353 |
ABT-751(E 7010)
Featured
ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 μM in neuroblastoma and non-neuroblastoma cell lines, respectively. |
141430-65-1 |
DC4186 |
Cabazitaxel
Cabazitaxel (Jevtana, XRP6258) is a semi-synthetic derivative of a natural taxoid. |
183133-96-2 |
DC11107 |
CKD-516
CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo. |
1188371-47-2 |
DC5134 |
lexibulin (CYT997)
CYT997 is a potent microtubule polymerization inhibitor with IC50 of 10-100 nM in cancer cell lines. Phase 1/2. |
917111-44-5 |
DC10953 |
DZ-2384
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types. |
1403850-91-8 |
DC4198 |
Epothilone B
Featured
Epothilone B is a Taxol-like microtubule-stabilizing agent with EC0.01 of 1.8 μM. |
152044-54-7 |
DCAPI1539 |
Eribulin Mesylate
Eribulin Mesylate |
441045-17-6 |
DCAPI1516 |
Eribulin
Eribulin Mesylate (E7389 Mesylate), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and microtubules. |
253128-41-5 |
DC5882 |
Fosbretabulin disodium
Featured
Fosbretabulin disodium(CA 4DP; CA 4P) is a microtubule destabilizing drug, a type of vascular-targeting agent, a drug designed to damage the vasculature (blood vessels) of cancer tumors causing central necrosis. |
168555-66-6 |
DCAPI1510 |
Ixabepilone
Featured
Ixabepilone (Azaepothilone B; BMS 247550) is an epothilone B analog and nontaxane microtubule-stabilizing compound with clinical activity in a range of solid tumors. |
219989-84-1 |
DC11241 |
MP-HJ-1b
MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation. |
|
DC7023 |
Ombrabulin
Featured
Ombrabulin (AVE8062) hydrochloride is a synthetic derivative of CA-4-P, which inhibits growth in a large number of drug-resistant animal tumors and carcinogen-induced tumors. |
181816-48-8 |
DC10981 |
Plocabulin
Plocabulin (PM060184) is a novel tubulin-binding agent binding to αβ-tubulin dimer with nanomolar affinity, inhibits a panel of 23 tumor cell lines with GI50 of 20 pM-5 nM. |
960210-99-5 |
DC11225 |
VERU-111
VERU-111 (VERU111) is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities. |
1332881-26-1 |
DC11227 |
VERU-111 analogue 13f
VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities. |
|
DC4184 |
Vinorelbine Ditartrate
Featured
Vinorelbine (Navelbine) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM. |
125317-39-7 |