Cat. No. | Product name | CAS No. |
DC10428 |
(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an PIM inhibitor extracted from patent US 20100056576 A1, compound example 72, has IC50 values of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3. |
|
DC8256 |
AS 602801(Bentamapimod)
Featured
AS 602801(Bentamapimod) is a novel, orally active inhibitor of JNK. |
848344-36-5 |
DC5012 |
AZD-1208
Featured
AZD1208 is orally available, small molecule inhibitor of PIM kinases with potential antineoplastic activity. |
1204144-28-4 |
DC9704 |
Unii-G55ZH52P57
Featured
BTZ043 is a inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), It can display nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro. |
1161233-85-7 |
DCAPI1392 |
BTZ043 racemate
Featured
BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. |
957217-65-1 |
DC7153 |
CX6258
Featured
CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity. |
1202916-90-2 |
DC10171 |
Hispidulin
Featured
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC50 of 2.71 μM. |
1447-88-7 |
DC10918 |
INCB053914
INCB053914 (INCB-053914) is a novel potent, and selective ATP-competitive, pan-PIM kinase inhibitor with IC50 of 0.24/30.0/0.12 nM for PIM1/2/3, respectively. |
1620012-39-6 |
DC10748 |
NSC31205
Featured
NSC 31205 is a PIM2/1 inhibitor. |
6320-51-0 |
DC9593 |
Pim1/AKK1-IN-1
PIM/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively; also inhibits MPSK1 and TNIK. |
1093222-27-5 |
DC10047 |
PIM-447 dihydrochloride
Featured
PIM447 is novel pan-PIM kinase inhibitor, including Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase. |
1820565-69-2 |
DC7236 |
Pimobendan
Featured
Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. |
74150-27-9 |
DC8604 |
Pim-1 Inhibitor 2
Potent Pim-1 kinase inhibitor (Ki = 91 nM). |
477845-12-8 |
DC7160 |
SGI-1776
Featured
SGI-1776 is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM; 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. |
1025065-69-3 |
DC10514 |
SMI-16a
Featured
SMI-16a is a selective Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively. |
587852-28-6 |
DC7503 |
SMI 4a
Featured
SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM, modest potent to Pim-2, does not significantly inhibit other serine/threonine- or tyrosine-kinases. |
438190-29-5 |
DC7514 |
TCS PIM-1 1
Featured
TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s >20,000 nM). |
491871-58-0 |
DC10031 |
TP-3654
Featured
TP-3654 is a small molecule pan-Pim (PIM) kinase inhibitor. |
1361951-15-6 |
DC11436 |
YLT-11
Featured
YLT-11 is a novel and specific PLK4 inhibitor with IC50 of 22 nM and Kd of 5.2 nM. |
|
DC44020 |
PIM1-IN-1
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity. |
1417630-95-5 |
DC45197 |
R8-T198wt
R8-T198wt is a cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. |
2305815-72-7 |
DC47380 |
MNK/PIM-IN-1
MNK/PIM-IN-1 represents an innovative dual MNK/PIM inhibitor with a good pharmacokinetic profile. |
2430792-91-7 |