Home > Inhibitors & Agonists > Autophagy > Salt Inducible Kinase (SIK)
Cat. No. Product name CAS No.
DC10824 ARN-3236 Featured

ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.

DC10778 YKL-06-061 Featured

YKL-06-061 is a potent and selective SIK (salt-inducible kinase) inhibitor.

DC46043 MRIA9

MRIA9 is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively.

DC46639 WH-4-025 Featured

WH-4-025 is a Salt-inducible kinase (SIK) inhibitor (WO2016023014 A2).

DC72558 GLPG3970

GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease.

DC73147 GLPG3312

GLPG3312 is a potent and selective pan-SIK inhibitor with IC50 of 2.0/0.7/0.6 nM for SIK1/SIK2/SIK3, respectively.

DC73148 JRD-SIK1/2i-4

JRD-SIK1/2i-4 is a potent, highly selective SIK1/2 inhibitor, modulates innate immune activation and suppress intestinal inflammation.

DC73149 SK-124

SK-124 (SK124) is a potent, selective, orally active SIK2/SIK3 inhibitor with IC50 of 8.8/11.3 nM in cell-based NanoBRET assays, 15-fold selectivity versus SIK1.

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