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Cat. No. Product name CAS No.
DC11547 LY-2562175 Featured

A novel potent, selective, partial FXR agonist with EC50 of 193 nM.

DCAPI1468 Rosuvastatin Calcium Featured

A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic.

DCAPI1442 Atorvastatin Calcium Featured

Atorvastatin Calcium

DC1094 Avasimibe Featured

Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively.

DC9252 BMS-687453 Featured

BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays.

DC11098 CKD-519

CKD-519 (Rocacetrapib, CKD519) is a potent, selective cholesteryl ester transfer protein (CETP) inhibitor, inhibits the CETP-mediated transfer of cholesteryl ester in human serum with IC50 of 2.3 nM.

DC7125 Evacetrapib (LY2484595) Featured

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.

DC7422 GSK1292263 Featured

GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes.

DC4233 GW501516 Featured

GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes.

DC1009 Laropiprant Featured

MK 0524 is a potent, selective DP1 receptor antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively.

DC10134 Obicetrapib (AMG-899,TA-8995) Featured

Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy.

DC11360 Pemafibrate Featured

Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis.

DC6903 Lapaquistat Acetate (TAK-475)

Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.

DC7933 Ro 48-8071 fumarate Featured

Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.

DC10700 Seladelpar Featured

Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist.

DCAPI1349 Simvastatin (Zocor) Featured

Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.

DC10386 Tenapanor Featured

Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively.

DC7040 WAY-362450 (XL335; Turofexorate isopropyl) Featured

WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia.

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