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Cat. No. Product name CAS No.
DC11547 LY-2562175 Featured

A novel potent, selective, partial FXR agonist with EC50 of 193 nM.

DCAPI1468 Rosuvastatin Calcium Featured

A selective, competitive inhibitor of HMG-CoA reductase, that is also antilipemic.

DCAPI1442 Atorvastatin Calcium Featured

Atorvastatin Calcium

DC1094 Avasimibe (CI-1011) Featured

Avasimibe inhibits ACAT and CYP2C9 with IC50 of 3.3 μM and 2.9 μM, respectively.

DC9252 BMS-687453 Featured

BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays.

DC11098 CKD-519

CKD-519 (Rocacetrapib, CKD519) is a potent, selective cholesteryl ester transfer protein (CETP) inhibitor, inhibits the CETP-mediated transfer of cholesteryl ester in human serum with IC50 of 2.3 nM.

DC7125 Evacetrapib (LY2484595) Featured

Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.

DC7422 GSK1292263 Featured

GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes.

DC4233 GW501516 Featured

GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes.

DC1009 Laropiprant (MK-0524) Featured

MK 0524 is a potent, selective DP1 receptor antagonist with Ki values of 0.57 nM and 0.75 µM for the DP1 and DP2 receptors, respectively.

DC10134 Obicetrapib (AMG-899,TA-8995) Featured

Obicetrapib is a CETP inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction of low-density lipoprotein cholesterol (LDL-C), alone and in combination with statin therapy.

DC11360 Pemafibrate Featured

Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis.

DC6903 Lapaquistat Acetate (TAK-475)

Protective effects of a squalene synthase inhibitor, lapaquistat acetate (TAK-475), on statin-induced myotoxicity in guinea pigs.

DC7933 Ro 48-8071 fumarate Featured

Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.

DC10700 Seladelpar Featured

Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist.

DCAPI1349 Simvastatin (Zocor) Featured

Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.

DC10386 Tenapanor Featured

Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively.

DC7040 WAY-362450 (XL335; Turofexorate isopropyl) Featured

WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia.

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