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Home > Inhibitors & Agonists > PI3K/Akt/mTOR > PIKfyve

PIKfyve

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Cat. No. Product Name Field of Application Chemical Structure
DC8275 Apilimod Featured
Apilimod(STA 5326) is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS–stimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM.
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DC74271 HZX-02-059
HZX-02-059 is a PIKfyve and tubulin dual-target inhibitor with high affinity for PIKfyve (Kd=10.4 nM), HZX-02-059 is a potent methuosis inducer, shows both in vitro and in vivo anti-tumor activity against TNBC.
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DC47381 MOMIPP Featured
MOMIPP, a macropinocytosis inducer, is a PIKfyve inhibitor. MOMIPP penetrates the blood-brain barrier (BBB).
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DC7343 YM201636 Featured
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110α.
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DC7922 APY0201 Featured
APY0201 is a potent, highly selective PIKfyve kinase inhibitor.
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