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Cat. No. Product name CAS No.
DC7815 Crisaborole(AN-2728) Featured

AN-2728 is a topically administered, boron-containing, anti-inflammatory compound that inhibits PDE4 activity and thereby suppresses the release of TNFalpha, IL-12, IL-23 and other cytokines.

DC10141 E6005 Featured

E6005 potently and selectively inhibited human PDE4 activity with an IC50 of 2.8 nM and suppressed the production of various cytokines from human lymphocytes and monocytes with IC50 values ranging from 0.49 to 3.1 nM.

DC10399 PAC-14028

PAC-14028 is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist.

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