Cat. No. | Product name | CAS No. |
DC6901 |
Daporinad(FK866,APO866)
Featured
APO866 effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 of 0.09 nM. |
658084-64-1 |
DC8139 |
GMX1778(CHS-828)
Featured
CHS-828 is a pyridyl cyanoguanidine anti-tumor agent that has been identified as a competitive inhibitor of Nampt as well as an inhibitor of NF-κB pathway activity. |
200484-11-3 |
DC10665 |
LSN3154567(Nampt-IN-1)
Featured
LSN3154567 is a novel inhibitor of NAMPT with IC50 of 18 nM (NCI-H1155 cell), 49 nM (Calu-6 cell), 333 nM (HCC1937 cell), and 389 nM (MCF-7 cell), respectively. |
1698878-14-6 |
DC7573 |
STF-118804
Featured
STF-118804 is a highly specific NAMPT inhibitor. |
894187-61-2 |
DC11492 |
GMX-1777 chloride
The water-soluble prodrug of GMX-1778 (CHS-828), which is a potent and specific inhibitor of the NAD(+) biosynthesis enzyme NAMPT with IC50 of <20 nM. |
432037-57-5 |
DC28672 |
Nampt-IN-5
Nampt-IN-5 is a potent and orally active nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 inhibits CYP3A4 activity and has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively. |
2380013-17-0 |
DC28969 |
GPP78
GPP78 (CAY10618) is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects. |
1202580-59-3 |