| Cat. No. | Product name | CAS No. |
| DC9456 |
MK-0354
MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b. |
851776-28-8 |
| DC9455 |
MK-6892
MK-6892 is a highly potential GPR109A agonist with Ki value of 4.0 nM. |
917910-45-3 |
| DC42499 |
GSK256073
GSK256073 is a potent, selective and orally active GPR109A agonist and a long-lasting and non-flushing HCA2 full agonist with a pEC50 of 7.5 (human HCA2). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis and has the potential for the study of type 2 diabetes mellitus (T2DM)and dyslipidemia. GPR109A: G-protein coupled receptor 109A; HCA2: hydroxy-carboxylic acid receptor 2 |
862892-90-8 |
