Cat. No. | Product name | CAS No. |
DC11507 |
CLP257
Featured
CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM; displays selectivity for KCC2 over other KCC family members, NKCC1 and GABAA receptors, and a panel of 55 other receptors; restores impaired Cl(-) transport in neurons, rescues KCC2 plasma membrane expression; renormalizes stimulus-evoked responses in spinal nociceptive pathways in a rat model of neuropathic pain. |
1181081-71-9 |
DC11173 |
DRAinh-A250
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA), fully and reversibly inhibits SLC26A3-mediated Cl- exchange with HCO3-, I-, and thiocyanate (SCN-) with IC50 of ~0.2 uM. |
858747-13-4 |
DC8601 |
IAA-94
IAA-94 is an indanyloxyacetic acid blocker of epithelial chloride channels. |
54197-31-8 |
DC12169 |
(N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide)
VU0463271 is a potent KCC2 antagonist, with an IC50 of 61 nM. |
1391737-01-1 |
DC29060 |
Picrotoxinin
Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. |
17617-45-7 |
DC42220 |
Fenamic acid
Fenamic acid is a chloride channel blocker. |
91-40-7 |