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Home > Molecular Glues

Asukamycin

  Cat. No.:  DC36190   Featured
Chemical Structure
61116-33-4
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More than 5000 active chemicals with high quality for research!
Field of application
Asukamycin, a macrolide polyketide derived from Streptomyces nodosus subsp. asukaensis, exhibits dual antimicrobial and antitumor activities. This natural product demonstrates broad-spectrum antibiotic properties while selectively inhibiting tumor cell proliferation through caspase-8/3-mediated apoptosis induction.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 61116-33-4
Chemical Name: Asukamycin
Synonyms: 2,4,6-Heptatrienamide,7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-,(2E,4E,6E)-;2,4,6-Heptatrienamide,7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-;2,4,6-Heptatrienamide,7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-7-oxo-1,3,5-heptatrien-1-yl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-,(2E,4E,6E);asukamycin;AM 1042;asukamycin A1;Manumycin F;2,4,6-Heptatrienamide, 7-cyclohexyl-N-(5-hydroxy-5-(7-((2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino)-7-oxo-1,3,5-heptatrienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-;(2E,4E,6E)-7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]hepta-2,4,6-trienamide;LMFA08020166;(2E,4E,6E)-7-cy;61116-33-4;Q27105012;CHEBI:73481;CS-0077603;AM 1042, AM1042, AM-1042, Asukamycin;HY-118893;BRN 3639742;DTXSID401318456;(2E,4E,6E)-7-cyclohexyl-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]hepta-2,4,6-trienamide;DA-60961;(2E,4E,6E)-7-cyclohexyl-N-((1S,5S,6R)-5-hydroxy-5-((1E,3E,5E)-7-((2-hydroxy-5-oxocyclopent-1-en-1-yl)amino)-7-oxohepta-1,3,5-trien-1-yl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)hepta-2,4,6-trienamide;(2E,4E,6E)-7-cyclohexyl-N-((1S,5S,6R)-5-hydroxy-5-((1E,3E,5E)-7-((2-hydroxy-5-oxocyclopenten-1-yl)amino)-7-oxohepta-1,3,5-trienyl)-2-oxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)hepta-2,4,6-trienamide
SMILES: O1[C@]2([H])C(C(=C([H])[C@@](/C(/[H])=C(\[H])/C(/[H])=C(\[H])/C(/[H])=C(\[H])/C(N([H])C3C(C([H])([H])C([H])([H])C=3O[H])=O)=O)([C@]12[H])O[H])N([H])C(/C(/[H])=C(\[H])/C(/[H])=C(\[H])/C(/[H])=C(\[H])/C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=O)=O
Formula: C31H34N2O7
M.Wt: 546.6109
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
TITLE DOWNLOAD
MSDS_18500_DC36190
COA
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