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Anavex-2-73

  Cat. No.:  DC33564   Featured
Chemical Structure
195615-84-0
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More than 5000 active chemicals with high quality for research!
Field of application
Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated the scopolamine- and dizocilpine-induced learning impairments. ANAVEX2-73 (300 μg/kg) also reversed the learning deficits in mice injected with Aβ(25-35) peptide, a non-transgenic Alzheimer's disease model. The neuroprotective activity of ANAVEX2-73, its mixed cholinergic/σ(1) activity, its low active dose range and its long duration of action together reinforce its therapeutic potential in Alzheimer's disease.
Cas No.: 195615-84-0
Chemical Name: Blarcamesine hydrochloride
Synonyms: ANAVEX 2-73;AVex-73 hydrochloride;AN2;AVEX-73 HCL SALT;AVex-73 hydrochloride salt;Blarcamesine hydrochloride;ANA001-HCl;Blarcamesine (hydrochloride);1-(2,2-diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride;Blarcamesine hydrochloride (USAN);Blarcamesine hydrochloride [USAN];1-(2,2-diphenyloxolan-3-yl)-N,N-dimethylmethanamine hydrochloride;Anavex-2-73
SMILES: Cl[H].O1C([H])([H])C([H])([H])C([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1(C1C([H])=C([H])C([H])=C([H])C=1[H])C1C([H])=C([H])C([H])=C([H])C=1[H]
Formula: C19H24ClNO
M.Wt: 317.8530
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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