Br-C3-methyl ester|CAS 4897-84-1|DC Chemicals

Cas No.:	4897-84-1
Chemical Name:	Methyl 4-bromobutyrate
Synonyms:	Methyl 4-bromobutanoate;4-Bromobutyric acid methyl ester;Methyl 4-bromobutyrate;METHYL-4-BROMOBUTYRATE;Butanoic acid, 4-bromo-, methyl ester;Methyl4-bromobutyrate;Butyric acid, 4-bromo-, methyl ester;Methyl gamma-bromobutyrate;4-brombutyric acid methyl ester;4-bromobutyric acid methyl-ester;QAWFLJGZSZIZHO-UHFFFAOYSA-;4-bromobutanoic acid methyl ester;4-bromobut;Br-C3-methyl ester
SMILES:	BrC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
Formula:	C₅H₉BrO₂
M.Wt:	181.0278
Purity:	>98%
Sotrage:	Pure form-20°C3 years4°C2 years In solvent-80°C6 months-20°C1 month

Cat. No.	Product name	Field of application
DC65211	KT-474	KT-474 is a highly active and selective, orally bioavailable IRAK4 degrader being developed for the treatment of toll-like receptor (TLR)/interleukin-1 receptor (IL-1R)-driven immune-inflammatory diseases.
DC39826	Homo-PROTAC cereblon degrader 1	Homo-PROTAC cereblon degrader 1, is a cereblon degrader.
DC74523	XY-07-35	XY-07-35 is a potent, selective HDAC6 proteolysis targeting chimera (PROTAC) degrader with IC50 of 48.5 nM.
DC74496	HJM-561	HJM-561 is a potent, selective and orally bioavailable EGFR PROTAC degrader, selectively degrades the EGFR C797S-containing triple mutants Del19/T790M/C797S and L858R/T790M/C797S with DC50 values of 9.2 nM and 5.8 nM, respectively.
DC74494	GNE-0011	GNE-0011 is a monovalent, JQ1-based BRD4 degrader that is not linked to an E3 ligase binder, triggers proteasomal and ubiquitin-dependent selective degradation of BRD4 over BRD2 and BRD3.
DC74479	BSJ-05-037	BSJ-05-037 is a potent and selective heterobifunctional degrader of ITK with DC50 of 17.6-41.8 nM in TCL lines DERL-2 and Hut78.
DC72756	JQAD1	JQAD1 is a CRBN-dependent PROTAC that selectively targets EP300 for degradation. JQAD1 suppresses EP300 expression and the H3K27ac modification. JQAD1 induces apoptosis. JQAD1 can be used in research of cancer.
DC50038	PROTAC SGK3 degrader-1	PROTAC SGK3 degrader-1 (SGK3-PROTAC1), is a potent SKG3 degrader based on PROTAC. PROTAC SGK3 degrader-1 (0.3 μM) induces 50% degradation of endogenous SGK3 within 2 hours, with maximal 80% degradation observed within 8 hours, accompanied by a loss of phosphorylation of NDRG1 (an SGK3 substrate).
DC48434	TD-165	TD165(TD 165) is a PROTAC-based cereblon (CRBN) degrader that degrads Cav1.2α with the DC50 of 20.4 nM, comprising a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group.
DC47072	PROTAC PTK6 ligand-1	PROTAC PTK6 ligand-1 is an intermediate for BTK kinase inhibitor preparation. PROTAC PTK6 ligand-1 can be used in the synthesis of ARD-61.