KH7|cas 330676-02-3|DC Chemicals

Cas No.:	330676-02-3
Chemical Name:	(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Synonyms:	(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;KH 7;2-(1H-benzimidazol-2-ylsulfanyl)-N'-[(Z)-(3-bromo-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]propanehydrazide;AC1OBAO2;AGN-PC-005XAZ;CTK8E6712;(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide
SMILES:	BrC1C=CC(=O)/C(=C/NNC([C@@H](SC2=NC3=CC=CC=C3N2)C)=O)/C=1
Formula:	C₁₇H₁₅BrN₄O₂S
M.Wt:	419.295601129532
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays[1].
Target:	IC50: 3-10 μM (recombinant sACt)[1].
References:	[1]. Hess KC, et al. The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Dev Cell. 2005 Aug;9(2):249-59.

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