5F 203|CAS 260443-89-8|NSC 703786|DC Chemicals

Cas No.:	260443-89-8
Chemical Name:	4-(5-Fluorobenzothiazol-2-yl)-2-methylphenylamine
Synonyms:	4-(5-Fluorobenzothiazol-2-yl)-2-methylphenylamine;NSC-D703786;NSC-703786;5F-DF-203;5F-203;4-(5-fluoro-1,3-benzothiazol-2-yl)-2-methylaniline;5-Fluoro 203;4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine;5F203;NCS 703786;NSC 703786
SMILES:	FC1=CC2N=C(C3C=CC(N)=C(C)C=3)SC=2C=C1
Formula:	C₁₄H₁₁FN₂S
M.Wt:	258.313945055008
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A potent, selective antitumour agent through activation the aryl hydrocarbon receptor (AhR) pathway; causes MCF-7 sensitive cells to arrest in G(1) and S phase, and induces DNA adduct formation, in contrast to AhR-deficient AH(R100) variant MCF-7 cells, induces CYP1A1 and CYP1B1 transcription; L-lysylamide prodrug Phortress (NSC 710305) demonstrats antitumor activity in vivo.

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