Cas No.: | 433690-62-1 |
Chemical Name: | AA41612 |
Synonyms: | 1-(2,5-Dichloro-4-methoxyphenylsulfonyl)piperidine;1-[(2,5-Dichloro-4-methoxyphenyl)sulfonyl]piperidine |
SMILES: | COC1=CC(Cl)=C(S(N2CCCCC2)(=O)=O)C=C1Cl |
Formula: | C12H15NO3Scl2 |
M.Wt: | 324.223 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner; specifically and reversibly modifies melanopsin-dependent light responses including the pupillary light reflex and light aversion in vivo. |