| Cas No.: | 83027-13-8 |
| Chemical Name: | N,N'-Bis(diphenylmethyl)-1,2-ethanediamine |
| Synonyms: | AMN082;AMN-082 |
| Formula: | C28H28N2 |
| M.Wt: | 392.546 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A potent, selective mGluR7 allosteric agonist that inhibits forskolin-stimulated cAMP accumulation in mGluR7b CHO cells with EC50 of 64±32 nM; displays no activating or inhibitory effects at other mGluR subtypes and ionotropic GluRs; potently inhibits cAMP accumulation and stimulates GTPgammaS binding with EC50 of 64-290 nM; elevates the plasma stress hormones corticosterone and corticotropin in an mGluR7-dependent fashion in vivo. |

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