Cas No.: | 479413-68-8 |
Chemical Name: | 12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid |
SMILES: | OC(=O)CCCCCCCCCCCNC(=O)NC1CCCCC1 |
Formula: | C19H36N2O3 |
M.Wt: | 340.5 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively; blocks conversion of 1 uM 14,15-EET to 14,15-DHET by 94% at 10 uM in COS-7 cells; activates PPARα 8-fold at a concentration of 10 uM but exhibits no affect on PPARδ or PPARγ. |