Cas No.: | 2610-05-1 |
Chemical Name: | Tetrasodium;(6E)-4-amino-6-[[4-[4-[(2E)-2-(8-amino-1-oxo-5,7-disulfonatonaphthalen-2-ylidene)hydrazinyl]-3-methoxyphenyl]-2-methoxyphenyl]hydrazinylidene]-5-oxonaphthalene-1,3-disulfonate |
Synonyms: | Direct Blue 1;Pontamine sky blue;p-425;p425 |
SMILES: | [Na+].[Na+].[Na+].[Na+].COC1C=C(C2=CC=C(/N=N/C3C=CC4=C(S([O-])(=O)=O)C=C(C(N)=C4C=3O)S([O-])(=O)=O)C(OC)=C2)C=CC=1/N=N/C1=CC=C2C(S([O-])(=O)=O)=CC(=C(N)C2=C1O)S([O-])(=O)=O |
Formula: | C34H24N6Na4O16S4 |
M.Wt: | 992.791 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry, also is the first small molecule prion protein (PrP) ligand capable of inhibiting Aβ binding; inhibits Aβ binding and reduce prion levels was established in cell-based assays; also is a competitive VGLUT inhibitor without affecting plasma membrane transporters, shows antinociceptive effects in vivo; also is an allosteric inhibitor of macrophage migration inhibitory factor (MIF) with IC50 of 0.81 uM. |