F16| CAS 36098-33-6

Cas No.:	36098-33-6
Chemical Name:	F16
Synonyms:	Pyridinium,4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-, iodide (9CI);3-[2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole,iodide;F16;4-[(E)-2-(1H-INDOL-3-YL)-VINYL]-1-METHYL-PYRIDINIUM;F-16;IN1341;MS-25743;SR-01000485413-3;HMS3648A09;NSC-158021;4-[(E)-2-(1H-INDOL-3-YL)-VINYL]-1-METHYL-PYRIDINIUM; IODIDE;26608-75-3;4-[(E)-2-(Indol-3-yl)ethenyl]-N-methylpyridinium iodide;MLS000557147;HMS2542C03;3-[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-1H-indole;iodide;36098-33-6;NSC158021;(e)-4-(1h-indol-3-ylvinyl)-N-methylpyridinium iodide;SMR000178707;4-[(E)-2-(1H-Indol-3-yl)-vinyl]-1-methyl-pyridinium;SCHEMBL17270524;(E)-4-(3-indolylvinyl)-N-methylpyridinium iodide;F85403;CHEMBL1485211;AKOS027469358;HY-100395;CS-5707
SMILES:	C[N+]1=CC=C(/C=C/C2=CNC3=C2C=CC=C3)C=C1.[I-]
Formula:	C₁₆H₁₅N₂+^.CH₄
M.Wt:	251.34616
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A mitochondriotoxic small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines; inhibits oxidative phosphorylation and inducing mitochondrial transmembrane depolarization, induce apoptosis and necrosis in a variety of tumor cells.

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