Peretinoin| CAS 81485-25-8

Cas No.:	81485-25-8
Chemical Name:	2,4,6,10,14-Hexadecapentaenoic acid, 3,7,11,15-tetramethyl-, (2E,4E,6E,10E)-
Synonyms:	NIK-333;NIK333;NIK 333
SMILES:	C/C(=C/CC/C(=C/CC/C(=C/C=C/C(=C/C(=O)O)/C)/C)/C)/C
Formula:	C₂₀H₃₀O₂
M.Wt:	302.451
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

A novel orally available, synthetic retinoid with potential antineoplastic and chemopreventive activities; inhibits DEN-induced rat hepatocarcinogenesis through suppression of TGF-alpha expression and cell proliferation; decreases the levels of cyclin D1, cyclin D2, cIAP2 and XIAP proteins, and inhibits growth of ATL cells both in vitro and in vivo; prevents the progression of NASH and the development of HCC through activating the autophagy pathway by increased Atg16L1 expression in mice model; also inhibits HCV replication and infectious virus release in vitro.Liver CancerPhase 3 Clinical

Cat. No.	Product name	Field of application
DC47250	Nonanal	Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity.
DC47249	Piperitone	Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity.
DC47247	Tyrosylleucine TFA	Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47243	Dehydroglyasperin C	Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
DC47227	(−)-Myrtenal	(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats.
DC47224	GPX4-IN-3	GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
DC47179	Tyrosylleucine	Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47178	Mead acid	Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency.
DC47140	Yadanzioside K	Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105	Complanatoside B	Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.