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Lenalidomide hydrochloride

  Cat. No.:  DC67354   Featured
Chemical Structure
1243329-97-6
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More than 5000 active chemicals with high quality for research!
Field of application
Lenalidomide hydrochloride (CC-5013 hydrochloride), a thalidomide-derived molecular glue, functions as an orally bioavailable immunomodulatory agent. By binding to the ubiquitin E3 ligase cereblon (CRBN), it recruits the CRBN-CRL4 complex to induce selective ubiquitination and degradation of lymphoid transcription factors IKZF1 and IKZF3. This mechanism underlies its potent activity against mature B-cell malignancies, including multiple myeloma, while also stimulating IL-2 secretion from T cells.
Cas No.: 1243329-97-6
Chemical Name: Lenalidomide (hydrochloride)
Synonyms: Lenalidomide (hydrochloride);CC-5013 hydrochloride;CC5013 hydrochloride;CC 5013 hydrochloride;RevliMid hydrochloride;Lenalidomide HCl;UNII-46Q7T54YCJ;1243329-97-6;Lenalidomidehydrochloride;AKOS030526351;RYWZLJSDFZVVTD-UHFFFAOYSA-N;DA-64913;Lenalidomide hydrochloride;3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione hydrochloride;HY-A0003A;3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione hydrochloride;SCHEMBL1904696;TQR1045;3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione;hydrochloride;2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-, hydrochloride (1:1);46Q7T54YCJ;CS-1589
SMILES: O=C1C2=CC=CC(N)=C2CN1C(C(N3)=O)CCC3=O.[H]Cl
Formula: C13H14ClN3O3
M.Wt: 295.721561908722
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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