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Etelcalcetide Hydrochloride(AMG-416)

  Cat. No.:  DC8189   Featured
Chemical Structure
1334237-71-6
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More than 5000 active chemicals with high quality for research!
Field of application
Etelcalcetide (AMG 416) is a novel, long-acting selective peptide agonist of the calcium sensing receptor, activates calcium sensing receptor on parathyroid glands reducing PTH synthesis and secretion.
Cas No.: 1334237-71-6
Chemical Name: N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride
Synonyms: AMG 416, KAI-4169, velcalcetide hydrochloride,Parsabiv,AMG416, 1262780-97-1 (free base)
SMILES: C[C@@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC([C@H](NC(C)=O)CSSC[C@H](N)C(O)=O)=O)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)C(N[C@@H](C(N)=O)CCCNC(N)=N)=O
Formula: C38H73N21O10S2.HCl
M.Wt: 1084.71
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].
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