Cas No.: | 51987-99-6 |
Chemical Name: | N-1,3,4-Thiadiazol-2-yl-3-pyridinecarboxamide |
Synonyms: | TGN 020,TGN-020,TGN020,51987-99-6 |
SMILES: | O=C(NC1=NN=CS1)C2=CN=CC=C2 |
Formula: | C8H6N4Os |
M.Wt: | 206.22 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
In Vitro: | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |