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BU72

  Cat. No.:  DC76607  
Chemical Structure
173265-76-4
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More than 5000 active chemicals with high quality for research!
Field of application
BU72 is a highly potent and long-acting agonist of μ and κ opioid receptors, and also has a partial agonist effect on δ opioid receptors (EC50 values are 0.054, 0.033, and 0.58 nM, respectively). BU72 has a strong and long-lasting analgesic effect, which is mainly mediated by μ opioid receptors. BU72 has a long-lasting activity and can partially reverse the analgesic effect of morphine. BU72 can be used in the study of opioid dependence.
Cas No.: 173265-76-4
Chemical Name: BU72
SMILES: CO[C@@]12[C@](N[C@@H]3C4=CC=CC=C4)([H])[C@@](C5=CC(O)=CC=C5C[C@@]6([H])N7C)(CC7)C6(C=C2)CC13C
Formula: C28H32N2O2
M.Wt: 428.57
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
DC72634 (Rac)-SNC80 (Rac)-SNC80 is a racemate of SNC80. SNC80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist with a Ki of 1.78 nM and an IC50 of 2.73 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 has the potential for multiple headache disorders treatment.
DC46693 DAMGO DAMGO (DAGO) is a potent and selective μ opioid receptor agonist with ki of 17 nM.
DC44976 LY2940094 tartrate LY2940094 (BTRX-246040) tartrate is a potent, brain penetrant, selective and orally available N/OFQ peptide (NOP) receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 tartrate reduces Ethanol self-administration and Ethanol seeking in animal models.
DC41767 Nociceptin(1-7) TFA Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin. Nociceptin (1-7) TFA is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo.
DC41766 Nociceptin(1-7) Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin. Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo.
DC40982 Loperamide phenyl Loperamide phenyl is an impurity of Loperamide. Loperamide is an opioid receptor agonist.
DC28780 LY2444296 LY2444296 is an orally bioavailable, high-affinity and selective short-acting kappa opioid receptor (KOPR) antagonist, with a Ki value of ∼1 nM. LY2444296 exhibits anti-anxiety like effects.
DC10290 PZM21 PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM.
DC9527 Methylnaltrexone (Bromide) Methylnaltrexone Bromide is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation.
DC9526 Meptazinol (hydrochloride) Meptazinol Hcl(WY-22811 Hcl) is a unique centrally active opioid analgesic.
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