ML019 (SID 7969543)|CAS 868224-64-0|DC Chemicals

Cas No.:	868224-64-0
Chemical Name:	SID 7969543
Synonyms:	Ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;isoquinolinone scaffold, 2;F1808-0160;2-[2-[(2,3-DIHYDROBENZO[1,4]DIOXIN-6-YLCARBAMOYL)METHYL]-1-OXO-1,2-DIHYDROISOQUINOLIN-5-YLOXY]PROPIONIC ACID ETHYL ESTER;SID7969543;CHEMBL259067;AC1N2RVQ;ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-7-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;Ethyl2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate;SID 7969543;ML019;Ethyl 2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate;ethyl 2-((2-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoate;SMR000017938;MLS000103673;MLS002152840;MLS006011674;GTPL5423;BDBM2;ETHYL 2-[[2-[2-[(2,3-DIHYDRO-BENZO[B][1,4]DIOXINE-6-YL)AMINO]-2-OXOETHYL]-1,2-DIHYDRO-1-OXO-5-ISOQUINOLINYL]OXY]PROPANOATE;S;ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate;HMS3263G15;HMS3263G15;HMS2246E14;HMS2246E14;cid_4076092;cid_4076092;MS-28223;MS-28223;Q27088800;Q27088800;BRD-A43885598-001-08-1;BRD-A43885598-001-08-1;SR-01000622833-4;SR-01000622833-4;HY-107404;HY-107404;BDBM28638;BDBM28638;ethyl 2-[(2-{[(2,3-dihydro-1,4-benzodioxin-6-yl)carbamoyl]methyl}-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy]propanoate;ethyl 2-[(2-{[(2,3-dihydro-1,4-benzodioxin-6-yl)carbamoyl]methyl}-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy]propanoate;NCGC00261682-01;NCGC00261682-01;SID7969543, >=98% (HPLC), solid;SID7969543, >=98% (HPLC), solid;DA-67584;DA-67584;Tox21_500997;Tox21_500997;ethyl 2-({2-[(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate;ethyl 2-({2-[(2,3-dihydro-1,4-benzodioxin-6-ylcarbamoyl)methyl]-1-oxo-1,2-dihydroisoquinolin-5-yl}oxy)propanoate;LP00997;LP00997;G13291;G13291;SID-7969543;CS-0028417;SID-7969543;EX-A7587;CS-0028417;AKOS024457632;EX-A7587;CHEBI:91707;AKOS024457632;HMS3413N10;CHEBI:91707;868224-64-0;DTXSID90399071;HMS3413N10;HMS3677N10;868224-64-0;NCGC00081778-04;DTXSID90399071;NCGC00081778-02;HMS3677N10;HMS1654L06;NCGC00081778-04;NCGC00081778-02;SDCCGSBI-0633774.P001;HMS1654L06;NCGC00081778-03;SDCCGSBI-0633774.P001;NCGC00081778-03
SMILES:	O(C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2C(N(C([H])=C([H])C=21)C([H])([H])C(N([H])C1C([H])=C([H])C2=C(C=1[H])OC([H])([H])C([H])([H])O2)=O)=O
Formula:	C₂₄H₂₄N₂O₇
M.Wt:	452.4566
Purity:	>98%
Sotrage:	0°C (short term), -20°C (long term), desiccated

Cat. No.	Product name	Field of application
DC31074	Isopropyl myristate	Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC75868	AZ14133346	AZ14133346 (compound 36) is a potent and selective inhibitor of EGFR Exon20 insertions, with the IC50 of 85 nM. AZ14133346 plays an important role in cancer research.
DC75865	TI17	TI17 represents a novel class of targeted anticancer agents that specifically disrupt DNA damage repair mechanisms in malignant cells.
DC75816	Nisoxetine	Nisoxetine acts as a highly selective and potent noradrenaline transporter (NET) antagonist, exhibiting a binding affinity (Kd) of 0.76 nM. In addition to its antidepressant properties, nisoxetine functions as a local anesthetic by inhibiting voltage-gated sodium channels. This dual pharmacological activity makes it a compound of interest for both neurological and pain management research.
DC75641	GENZ-644282 TFA salt	Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
DC75325	PSMA-617 TFA	PSMA-617, also know as vipivotide tetraxetan, is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
DC75202	Fosaprepitant free acid	Fosaprepitant, also known as MK0517, is an antiemetic drug, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. Fosaprepitant is a weak inhibitor of CYP3A4, and aprepitant, the active moiety, is a substrate, inhibitor, and inducer of CYP3A4
DC74748	O4I4	O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
DC74684	ZH8667	ZH8667 is a trace amine-associated receptor 1 (TAAR1)–Gs agonist.
DC74646	EB-PSMA-617	EB-PSMA-617 is an Evans blue-modified prostate-specific membrane antigen (PSMA) 617 ligand for making 177Lu-EB-PSMA, which is potential useful for Metastatic Castration-Resistant Prostate Cancer.