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Cx43 HC-IN-1

  Cat. No.:  DC80495  
Chemical Structure
183737-04-4
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More than 5000 active chemicals with high quality for research!
Field of application
Cx43 HC-IN-1 (Compound D4) is a selective and orally active inhibitor of connexin hemichannels (Cx43 HC). Cx43 HC-IN-1 effectively inhibits the hemichannel activity mediated by Cx43/Cx45 in denervated skeletal muscle fibers, significantly increasing the reinnervation rate of muscle fibers by neurons. Cx43 HC-IN-1 reduces neuroinflammation and neuronal overexcitation by inhibiting hemichannels in glial cells in the brain, and alleviates epilepsy in mice. Cx43 HC-IN-1 can be used for research on epilepsy and muscle diseases.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 183737-04-4
Chemical Name: Cx43 HC-IN-1
Formula: C14H20N6O5
M.Wt: 352.35
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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