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Paritaprevir dihydrate

  Cat. No.:  DC71964  
Chemical Structure
1456607-71-8
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More than 5000 active chemicals with high quality for research!
Field of application
Paritaprevir (ABT-450) dihydrate is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir dihydrate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 μM. Paritaprevir dihydrate is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir dihydrate can be enhanced by Ritonavir (a CYP450 inhibitor).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1456607-71-8
Chemical Name: Paritaprevir dihydrate
SMILES: O=C([C@]1(NC([C@@]2([H])N3C[C@H](OC4=C(C=CC=C5)C5=C6C(C=CC=C6)=N4)C2)=O)[C@H](/C=C\CCCCC[C@H](NC(C7=NC=C(C)N=C7)=O)C3=O)C1)NS(=O)(C8CC8)=O.O.O
Formula: C40H47N7O9S
M.Wt: 801.91
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36266_DC71964_1456607-71-8
COA
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Cat. No. Product name Field of application
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