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PSI-353661

  Cat. No.:  DC72291  
Chemical Structure
1231747-08-2
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More than 5000 active chemicals with high quality for research!
Field of application
PSI-353661 (GS-558093) is a purine nucleotide NS5B polymerase inhibitor against HCV infection (EC90: 8 nM). PSI-353661 can produce high concentrations of the active triphosphate in primary human hepatocytes.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1231747-08-2
Chemical Name: PSI-353661
SMILES: COC1=NC(N)=NC2=C1N=CN2[C@@H]([C@@](F)(C)[C@@H]3O)O[C@@H]3CO[P@@](N[C@@H](C)C(OC(C)C)=O)(OC4=CC=CC=C4)=O
Formula: C24H32FN6O8P
M.Wt: 582.52
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36742_DC72291_1231747-08-2
COA
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Cat. No. Product name Field of application
DC46625 HCV-IN-30 HCV-IN-30 (compound 48) is a HCV NS5A replication complex inhibitor, with IC50s of 901 and 102 nM for genotypes 1a and 1b replicons, respectively.
DC1008 Telaprevir (VX-950) Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.
DC9463 Tegobuvir (GS-9190; GS 333126) Tegobuvir (GS-9190; GS 333126) is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.
DC9462 R-7128(Mericitabine) R-7128(Mericitabine) is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes.
DC76056 Netanasvir Netanasvir, a NS5A inhibitor, possesses antiviral activity. Netanasvir can be used in the study for HCV study.
DC76055 ML283 ML283 is a HCV NS3 helicase inhibitor (IC50: 2.6 μM). ML283 also inhibits DenV ATPase (IC50: 4.0 μM).
DC76054 Encofosbuvir Encofosbuvir is the inhibitor for HCV NS5B polymerase that inhibits GT1b, GT2a and GT3a with EC50 of 102.4, 82.51 and 46.91 nM. Encofosbuvir inhibits HCV replication and can be used for reseearchs of hepatitis C in mammals.
DC76053 3′-Deoxy CTP trisodium 3′-Deoxy CTP trisodium is the sodium salt form of 3′-Deoxy CTP. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid.
DC76052 3′-Deoxy CTP 3′-Deoxy CTP is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs.
DC72543 CL-197 CL-197 is an orally active and long-acting purine anti-HIV nucleoside reverse transcriptase inhibitor (NRTI). CL-197 has potential effect on the research of viral, oncological and cerebrovascular diseases.
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