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Antibody Drug Conjugates

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Cat. No. Product Name Field of Application Chemical Structure
DC29161 N-Boc-PEG3-bromide
N-Boc-PEG3-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29156 Fmoc-NH-PEG4-CH2CH2COOH
Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29025 Fmoc-Gly-Gly-Phe-OtBu
Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29024 MAC glucuronide linker-2
MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29023 MAC glucuronide linker-1
MAC glucuronide linker-1 is a nonclaevable ADC linker for antibody-drug-conjugations (ADCs).
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DC29022 m-PEG2-Tos
m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29021 Boc-NH-PEG4-CH2COOH
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
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DC29020 Azido-PEG4-CH2-Boc
Azido-PEG4-CH2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC29018 N3-PEG3-CH2CH2-Boc
N3-PEG3-CH2CH2-Boc is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-PEG3-CH2CH2-Boc is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
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DC29017 Hydroxy-PEG3-(CH2)2-Boc
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196).
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DC29015 BMPS
BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29014 Mal-L-PA-NH-Boc
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC29012 Mal-amido-(CH2COOH)2
Mal-amido-(CH2COOH)2, compound 7a, is a maleimidoethyl-containing intermediate for hydrophilic ADC linker.
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DC29011 NH-bis(C1-Boc)
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).
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DC28907 MMAE-SMCC
MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate.
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DC28861 Fmoc-Asp-NH2
Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28770 DC44
DC44, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44 can be used for the targeted treatment of cancer.
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DC28769 DC4
DC4, a ADC cytotoxin, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4 can be used for the targeted treatment of cancer.
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DC28768 DC44SMe
DC44SMe, a phosphate prodrug of cytotoxic DNA alkylator DC44, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer.
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DC28767 DC4SMe
DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer.
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DC28766 DC10SMe
DC10SMe is a DNA alkylator, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC10SMe exhibits IC50s of 15 pM, 12 pM, and 12 pM for Ramos, Namalwa, and HL60/s cancer cells, respectively.
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DC28720 Fmoc-NH-PEG8-CH2COOH
Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28719 Fmoc-NH-PEG5-CH2COOH
Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28699 Gemcitabine-O-Si(di-iso)-O-Mc
Gemcitabine-O-Si(di-iso)-O-Mc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28698 DBCO-Sulfo-Link-biotin
DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28685 Thalidomide-NH-PEG7
Thalidomide-NH-PEG7 is a synthesized E3 ligase ligand-linker conjugate for ADC. Thalidomide-NH-PEG7 can be connected to the ligand for protein by a linker to form PROTAC iRucaparib-AP6, a highly specific PARP1 degrader.
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DC28668 Propargyl-PEG4-Br
Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28666 m-PEG9-Amine
m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28665 Hydroxy-PEG3-SS-PEG3-alcohol
Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28663 m-PEG7-Ms
m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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