Prostaglandin K1 (compound 46) is a structurally modified analog of prostacyclin (prostanoid) with an EC50 of 2800 nM for EP1 and a Ki of 2800 nM.

Prostaglandin E1 isopropyl ester is an isopropyl ester form of prostaglandin E1. Prostaglandin E1 isopropyl ester exhibits a faster penetration flux than prostaglandin E1.

PGF2α analogue-1 is an analog of Dinoprost. Z-CITCO is an agonist of constitutive androstane receptor (CAR) with an EC50 value of 3.9 µM.

ONO-AE3-208 (sodium salt) is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM. ONO-AE3-208 (sodium salt) shows less potently affects EP3, FP, and TP receptors (Ki of 30 nM, 790 nM, and 2400 nM, respectively). ONO-AE3-208 (sodium salt) suppresses cell invasion, migration, and metastasis of prostate cancer.

O-Acetylsalicylhydroxamic acid is an acetylation inhibitor of prostaglandin H2 synthase that can suppress PGE2 synthesis in the body and block the cyclooxygenase activity of PGHS in vitro. O-Acetylsalicylhydroxamic acid requires the presence of the active site residue Ser-529 to act on human PGHS-1; the S529A mutant is resistant to the inactivation effects of this inhibitor.

MED 27 is an inhibitor of thromboxane synthase and thromboxane A2 receptors. MED 27 can inhibit rat platelet aggregation at doses much lower than that of acetylsalicylic acid.

Latanoprost amide is a derivative of the F-prostaglandin (FP) receptor agonist Latanoprost.

L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, composed of (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-l-yl acetic acid. The IC50s of (-) and (+) configurations for TxA2 are 0.27 nM and 124 nM, respectively.

Irodanoprost is the agonist for prostaglandin receptor that can be used for research of osteogenesis-related diseases.

FK-788 is a PGI(2) and IP agonist with a strong anti-aggregation effect, with an IC50 of 18 nM and a high binding affinity for the human recombinant IP receptor, with a Ki value of 20 nM.

CAY10509 is a PGF2α analog and an inhibitor of the FP receptor with an IC50 of 30 nM. CAY10509 is promising for studying physiological regulatory mechanisms related to prostaglandins.

Carbaprostacyclin methyl ester is a methylated derivative of Carbacyclin.

AL-12180 is a potent and selective FP-receptor agonist with a Ki of 143 nM. AL-12180 stimulates the mobilization of intracellular Ca2+ in h-TM and h-CM cells with EC50s of 111 and 11 nM, respectively.

9-keto latanoprost is a derivative of the F-prostaglandin (FP) receptor agonist Latanoprost.

9-Keto tafluprost is a derivative of Tafluprost. Tafluprost is an anti-glaucoma prostaglandin (PG) analog.

8-iso Prostaglandin F1β is an isoprostane, that exhibits vasoconstrictive effect in neonatal porcine pulmonary arteries, pulmonary veins, and mesenteric arteries. 8-iso Prostaglandin F1β targets TXA2 receptor and exhibits the blood vessel contractile efficacy under the influence of tyrosine kinase and Rho kinase.

5-trans-Fluprostenol is a synthetic prostaglandin analogue.

5S(6R)-EET is the metabolite of Arachidonic acid. 5S(6R)-EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na+ absorption, increases the intracellular Ca2+, and promotes the depolarization of transmembrane voltage. 5S(6R)-EET is more active than 5R(6S)-EET.

5R(6S)-EET is the metabolite of Arachidonic acid. 5R(6S)-EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na+ absorption, increases the intracellular Ca2+, and promotes the depolarization of transmembrane voltage. 5R(6S)-EET exhibits stereoselectivity with less effectness than 5S(6R)-EET.

2,3-Dinor thromboxane b1 is an urinary metabolite of Thromboxane B2 under physiological conditions. TXY541 has good antibacterial effect against Staphylococcus aureus and low toxicity to mammalian cells.

15-epi Prostaglandin A1 (15-epi PGA1) is the 15(R) stereoisomer of PGA1. PGA1 causes renal vasodilation, increased urine sodium excretion, and decreased arterial pressure in hypertensive models.

NSC380324 is a P2Y12 receptor antagonist, possessing antiplatelet activity, and can be utilized in research on atherosclerotic cardiovascular diseases.

MRS2905 (α,β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. MRS2905 trisodium is inactive at the UDP-activated P2Y6 receptor, and at other P2Y receptors.

Becondogrel (2-Oxoclopidogrel) is the metabolite of Clopidogrel, a dihydroorotate dehydrogenase (DHODH) inhibitor with antiviral activity.

β-Funaltrexamine (β-FNA) hydrochloride is a selective μ opioid receptor antagonist. β-Funaltrexamine hydrochloride also inhibits cytokine-induced iNOS activation. β-Funaltrexamine hydrochloride inhibits neuroinflammation and ameliorated neuronal degeneration. β-Funaltrexamine hydrochloride has anti-inflammatory and neuroprotective effects and can be used for research of neurodegenerative diseases (eg: stroke)[1][2]

U-49900 is a utopioid.

U-48520 is an agonist for μ-opioid receptor with EC50 of 1561 nM.

Samidorphan isoquinoline dioxolane (Compound 16) is a cyclazocine analogue with opioid receptor binding properties.

Salvinorin A (Divinorin A) propionate is a potent, unique and short-acting high efficacy kappa-opioid receptor (KOPr) agonist with Ki value of 4.3 nm. Salvinorin A propionate is a non-nitrogenous neoclerodane isolated from Salvia divinorum.

Salvinorin A carbamate is an agonist for κ-opioid receptor with an EC50 of 6.2 nM and a Ki of 3.2 nM.