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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC28666 m-PEG9-Amine
m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28665 Hydroxy-PEG3-SS-PEG3-alcohol
Hydroxy-PEG3-SS-PEG3-alcohol is also a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28664 Azido-PEG6-alcohol
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28663 m-PEG7-Ms
m-PEG7-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28662 Amino-PEG4-CH2COOH
Amino-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Amino-PEG4-CH2COOH is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28658 Cdc7-IN-4
Cdc7-IN-4 (compound I-C) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-C. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.
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DC28657 Cdc7-IN-3
Cdc7-IN-3 (compound I-A) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-B. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.
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DC28656 N-Boc-PEG7-alcohol
N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28655 N-Boc-PEG2-bromide
N-Boc-PEG2-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28653 Azido-PEG9-acid
Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28652 Azido-PEG6-NHS ester
Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs.
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DC28651 m-PEG4-Ms
m-PEG4-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28650 N-Boc-N-bis(PEG4-OH)
N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28648 DBCO-PEG4-amine
DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker).
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DC28647 Maleimido-tri(ethylene glycol)-propionic acid
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionic acid is used for the preparation of neolymphostin-based ADC precursors for site-specific cysteine mutant trastuzumab-A114C conjugation.
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DC28646 m-PEG6-Amine
m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28645 Propargyl-PEG4-C2-NHS ester
Propargyl-PEG4-C2-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28644 Propargyl-PEG6-NHS ester
Propargyl-PEG6-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28643 Propargyl-PEG7-NHS ester
Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28642 Propargyl-PEG8-bromide
Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28641 Propargyl-PEG8-NHS ester
Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28640 Propargyl-PEG9-bromide
Propargyl-PEG9-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28639 Fmoc-NH-PEG6-CH2COOH
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28638 Dibutyryl-cGMP sodium
Dibutyryl-cGMP sodium (Bt2cGMP sodium) is a cell-permeable cGMP analogue. Dibutyryl-cGMP sodium preferentially activates cGMP-dependent protein kinase (PKG). Dibutyryl-cGMP sodium inhibits the release of [3H]-arachidonic acid from γ thrombin-stimulated human platelets. Dibutyryl-cGMP sodium induces peripheral antinociception via activation of ATP-sensitive K+ channels.
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DC28636 DBCO-PEG4-DBCO
DBCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28635 NH-bis-PEG2
NH-bis-PEG2 is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28633 Br-PEG4-C2-Boc
Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28632 Amino-PEG11-OH
Amino-PEG11-OH is non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC28631 Propargyl-PEG4-CH2CH2-Boc
Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3.
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DC28630 HIF-2α-IN-2
HIF-2α-IN-2 is a hypoxia-inducible factors (HIF-2α) inhibitor extracted from patent WO2015035223A1, Compound 232, has an IC50 of 16 nM in scintillation proximity assay (SPA).
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