Novel potent apoptotic inducer of human leukaemia cells by activation of the extrinsic pathway and the generation of reactive oxygen species

Novel inhibitor of SARS-CoV-2 main protease (MPro)

Potent inhibitor of LpxC

Novel potent TRPM8 antagonist (IC 50 1.25 ± 0.26 μM)

Novel inhibitor of prion replication

Selective inhibitor of type A monoamine oxidase with dopaminergic properties

Novel potent and selective acetyl-CoA carboxylase (ACC) inhibitor, blocking WNT3A lipidation, secretion, and signaling

Novel potent and selective acetyl-CoA carboxylase (ACC) inhibitor

Negaitve control for BAY-390

Novel allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model

Negative control for BAY-678, a potent and selective human neutrophil elastase (HNE) inhibitor

Negative control for BAY-549

Novel allosteric MEK inhibitor with long half-lives, high bioavailabilities, low brain penetration potential and high efficacy in a K-Ras-mutated A549 xenograft model

Control compound for BAY-598, a novel potent inhibitor of SMYD2

Negative control for BAY299

Novel potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC 50 of 3 nM)

Negative control for BAY-3153

Novel MNK1 inhibitor, targeting oncogenic protein expression and showing potent anti-tumor activity

Negative control for BAY-091

Novel glucagon receptor antagonist

Novel cell-permeable synthetic peptide inhibitor of Bax, blocking apoptosis

Anticancer agent; inhibitor of BMP2K (BIKE) and DRAK1

Novel fluorescent Bortezomib-GV1001 conjugate for monitoring the delivery of the proteasome inhibitor bortezomib (Btz) to HT-29 cancer cells, exhibiting an improved cytoplasmic availability

The first small molecule inhibitor of Lipid II

Bile acid transporter inhibitor

Inhibitor of tumor angiogenesis, growth and metastasis in melanoma

Natural anti-breast cancer and anti-angiogenic agent

Antimalarial; Novel Chloroquine analog against Chloroquine-Resistant Parasites

Hypoxia-activated prodrug of topoisomerase II inhibitor

Novel BAM complex inhibitor, interferring with BamA-related processes and affect folding and insertion of OMPs