Memantine is an amantadine derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent and has may be used to treat moderate to severe Alzheimer's disease. It acts on the glutamatergic system by blocking NMDA receptors.

endo-BCN-PEG2-acid is a PEG derivative containing a BCN group with carboxylic acid in the terminal. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The BCN group can react with azide-tagged biomolecules.

NVS-CECR2-1 is a potent and selective CECR2 inhibitor.

Nagilactone B is a unique selective LXR regulator which suppresses atherosclerosis in apoE-deficient mice via promotion of cholesterol efflux in macrophages.

Fluazacort is an anti-inflammatory.

L-4FPG is an inhibitor of the neutral amino acid transporters ASCT1 and ASCT2. L-4FPG shows good brain penetration and potently reduces amphetamine-induced hyperlocomotion.

Purpurea glycoside A is a cardiac glycoside analog.

Purpurea glycoside B is a cardiac glycoside.

Trazodone hydrochloride is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders.

m-PEG12-amine is a PEG derivative containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates.

Oleanolic acid acrylate (OAA) is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A and a derivative of oleanolic acid. It is also a selective inhibitor of MAO-A with anti-depressant-like and anxiolytic activities.

m-PEG4-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG spacer increases solubility in aqueous media.

Methiothepin Maleate is an inhibitor of HCV infection and cell-to-cell transmission that acts by targeting the HCV E2 glycoprotein.

Picromycin is a 14-membered macrolide antibiotic and inhibitor of Prolyl endopeptidase (PREP). Pikromycin shows activity against gram-positive bacteria including mycobacteria.

Amino-PEG10-acidis a PEG derivative containing an amino group with a terminal carboxylic acid. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Propargyl-PEG1-SS-PEG1-propargyl is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG Linker.

Azido-PEG3-phosphonic acid is a PEG derivative containing an azide group and a phosphonic acid. The azide group enables Click Chemistry andthe phosphonic acid can be a potential ligand choice. The hydrophilic PEG spacer increases solubility in aqueous media.

NH-bis(PEG2-t-butyl ester) is a PEG derivative containing an amino group with two t-butyl esters. The amino groups is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates.

Aspergillimide is a fungal metabolite that reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.

A 127722 is highly potent and a selective ETA endothelin receptor antagonist (IC50 values are 0.11 nM and 98 nM for human ETA and ETB receptors, respectively)that attenuates hypoxia-induced pulmonary hypertension in rats.

NBD-Pen high-sensitivity, specific fluorescence probe for lipid radicals. NBD-Pen directly detected lipid radicals in living cells by turn-on fluorescence. In a rat model of hepatic carcinoma induced by diethylnitrosamine (DEN), NBD-Pen detected lipid radical generation within 1 hour of DEN administration.

Chloramben-sodium is an herbicide.

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7?. The alkyne can be conjugated to a variety of azides via copper-catalyzed Click chemistry. The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

3-Hydroxydecanoic acid, (3R)- is active against Bacillus subtilis, Escherichia coli and Staphyllococcus aureus. fungistatic activity against Candida albicans.

PDD 00017238 is a PARG inhibitor.

DBO-83 is an agonist of nicotinic acetylcholine receptors (nAChRs) with antinociceptive and anti-amnesic activities.

t-Boc-aminooxy-PEG3-propargyl is a crosslinker containing a propargyl group and t-Boc-aminooxy group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.

Bromo-PEG4-azide is a PEG derivative containing a bromide group and a terminal azide. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Propargyl-PEG6-acid is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.