XR-5000 (Acridine Carboxamide.

XR 5118 is a small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 3.5 uM, binds to PAI-1 and reduces plasma PAI-1 activity levels, promotes endogenous thrombolysis and inhibits thrombus accretion.

XMU-MP-2 is a potent and selective BRK/PTK6 (breast tumor kinase) inhibitor with biochemical IC50 of 3.2 nM.

XL-281 (BMS 908662) is a potent, selective, orally active inhibitor of wild-type and mutant RAF kinases with anti-tumor activity in multiple xenograft models.

XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus.

XEN-402 (Funapide.

Xanthyletin is a coumarin isolated from Citrus, with anti-tumor and anti-bacterial activities. Xanthyletin also inhibits symbiotic fungus cultivated by leaf-cutting ants.

Xamoterol (ICI 118587) is a third-generation adrenergic β1 adrenergic receptor partial agonist that acts as a cardiac stimulant..

Xamoterol (ICI 118587) is a third-generation adrenergic β1 adrenergic receptor partial agonist that acts as a cardiac stimulant..

WZ-4-49-8 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 67 nM.

WYE-151650 is a novel potent, selective JAK3 inhibitor with IC50 of 0.8 nM, displays 36-, 14-, and 34-fold selectivity against JAK-1, JAK-2, and Tyk-2, respectively.

WYC-209 is a novel synthetic retinoid that inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with IC50 of 0.19 uM, targets retinoic acid receptor (RAR).

WX-554 is an oral, small molecule allosteric inhibitor targeting mitogen-activated protein kinase kinase (MEK1 and MEK2) with an estimated IC50 of 4.7 and 10.7 nM, respectively.

WX-037 (UCB-1370037) is a novel small molecule pan class I PI3K inhibitor with IC50 of 4.1, 2.4, 37 and 78 nM for PI3Kα, PI3Kδ, PI3Kγ and PI3Kβ, respectively.

WWL113 is a potent inhibitor of Carboxylesterase Ces3 and Ces1f by competitive ABPP of enzymes recombinantly expressed in HEK293T cells (IC50 value of 0.1 uM for each enzyme).

WST-3 is a highly sensitive tetrazolium reagent (light red) which produces a water-soluble formazan (dark red color).

WS-383 hydrochloride (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM.

WS-383 (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM.

WRG-28 (DDR2 inhibitor WRG-28) is a potent, selective, allosteric inhibitor of discoidin domain receptor 2 (DDR2) with binding IC50 of 230 nM.

WOBE-437 (WOBE437) is a potent, selective endocannabinoid uptake inhibitor with IC50 of 10 nM, with an outstanding 1,000-fold selectivity over FAAH.

Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay.

Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis.1,2,3Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. IWP-2 (Item No. 13951) is an inhibitor of Wnt production (IC50 = 27 nM) that inactivates porcupine, a membrane-bound O-acyltransferase whose palmitoylation activity is essential For the signaling ability and secretion of Wnt proteins.4 IWP-2-V2 is a less potent IWP-2 derivative whose chemical structure retains the benzothiazole group of its parent compound.4 It has been used to determine which structural features of IWP-2 are essential For impairing Wnt/β-catenin pathway activity.4For the detailed information of IWP-2-V2, the solubility of IWP-2-V2 in water, the solubility of IWP-2-V2 in DMSO, the solubility of IWP-2-V2 in PBS buffer, the animal experiment (test) of IWP-2-V2, the cell expriment (test) of IWP-2-V2, the in vivo, in vitro and clinical trial test of IWP-2-V2, the EC50, IC50,and Affinity of IWP-2-V2, Please contact DC Chemicals..

Withaferin A is a steroid lactone that displays anti-inflammatory, antitumor and antiangiogenic activity, potently inhibits NF-κB activation by preventing the TNF-induced activation of IKKβ via a thioalkylation-sensitive redox mechanism.

WF-210 is a PAC-1 derivative and potent activator of procaspases-3 with EC50 of 0.95 uM, displays more cytotoxic than PAC‐1 to human cancer cells, but less cytotoxic to normal cells.

WEE1Hu inhibitor is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays.

WDR5-MLL1 inhibitor is a novel potent inhibitor of WDR5-MLL1 interaction, binds to WDR5 with Kd of 1 nM..

WDR5 WIN site inhibitor C6 is a potent, specific WIN (WDR5 interaction) site inhibitor of WDR5 with Kd of 0.1 nM.

WDR5 WIN site inhibitor C3 is a potent, specific WIN (WDR5 interaction) site inhibitor of WDR5 with Kd of 1.3 nM.

WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308); selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold).

WAY-362692 is a small molecule inhibitor of the secreted frizzled-related protein sFRP-1 with IC50 of 20 nM in FP binding assay.