Cat. No. | Product Name | Field of Application | Chemical Structure |
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DC12609 | VK4-116 |
VK4-116 is a novel potent, highly selective dopamine D3 receptor (D3R) antagonist with Ki of 6.8 nM, displays >1,000-fold selectivity over D2R.
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DC22257 | VK-1850 |
VK-1850 (VK1850) is a small-molecule inhibitor of the DNA binding activity of EBNA1 (Epstein-Barr nuclear antigen1).
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DC22256 | VK-1727 |
VK-1727 (VK1727) is a small-molecule inhibitor of the DNA binding activity of EBNA1 (Epstein-Barr nuclear antigen1).
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DC6503 | Vitamin B12 |
Vitamin B12 is a water-soluble vitamin with roles in brain and nervous system functioning and blood formation through regulation of DNA synthesis, cellular metabolism, fatty acid metabolism, and amino acid metabolism.
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DC12716 | VIS351 |
VIS351 (VIS-351) is a potent activator of the immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated function of the IDO1 enzyme with Kd of 1.9 uM.
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DC12559 | VinSpinIn |
VinSpinIn is a potent, cell active chemical probe for the Spin family protein with Kd of 10-130 nM for across the family, displays >300-fold selectivity over a panel of methyltransferases.
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DC23236 | Vinpocetine |
Vinpocetine (Ethyl apovincaminate) is a synthetic derivative of the vinca alkaloid vincamine, selectively inhibits PDE1 in isolated rabbit aorta with IC50 of 21 uM.
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DC7712 | Vilazodonei |
Vilazodone is an inhibitor of ST (serotonin transporter and uptake) (IC50 = 0.5 nM) and SR-1A activator (partial agonist) (IC50 = 0.2 nM; IA = ~60-70%).
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DC20741 | Vilaprisan |
Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator.
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DCAPI1248 | Vidarabine (Vira-A) |
Vidarabine (Vira-A)
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DC20579 | VHL-IN-15 |
VHL-IN-15 is a potent (IC50=4.1 uM) von Hippel–Lindau protein (VHL) ligand that disrupts the VHL/HIF-1α interaction..
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DC21968 | VHL-alkyne |
VHL-alkyne is a VHL ligand for PROTAC synthesis..
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DC26127 | VHL ligand 1 (TFA) |
VHL ligand 1 TFA is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
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DC21967 | VGTI-A3-03 |
VGTI-A3-03 is a novel potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM), directly bind DENV capsid protein.
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DC26108 | VGSC blocker 1 |
VGSC blocker 1 is a potent, small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5), blocks INa peak currents 34.9% at 1 uM.
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DC22417 | Vestipitant mesylate |
Vestipitant (GW597599) is a potent, selective, orally active NK1 receptor antagonist with pKi of 9.65.
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DC22423 | Vestipitant |
Vestipitant (GW597599) is a potent, selective, orally active NK1 receptor antagonist with pKi of 9.65.
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DC9599 | Vernakalant (Hydrochloride) |
Vernakalant Hcl(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic.
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DC9571 | Veratramine |
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.
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DC7880 | CP 16533-1 (Verapamil) |
Verapamil is a CYP3A inhibitor.
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DC9159 | Verapamil HCl |
Verapamil Hcl is an L-type calcium channel blocker of the phenylalkylamine class.
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DC5881 | Venlafaxine Hydro Chloride |
Venlafaxine Hydrochloride is a dual ST and SLC6A2 (serotonin and noradrenalin re-uptake) inhibitor that displays ~ 30-fold higher affinity for ST (SERT) (Ki = 82 nm) than SLC6A2 (NET) (Ki = 2480 nM).
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DC21744 | Velusetrag hydrochloride |
Velusetrag (TD-5108) is a potent, selective and oral 5-HT4 receptor agonist with pKi of 7.7, shows >500-fold selectivity over other 5-HT receptors.
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DC21743 | Velusetrag |
Velusetrag (TD-5108) is a potent, selective and oral 5-HT4 receptor agonist with pKi of 7.7, shows >500-fold selectivity over other 5-HT receptors.
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DC21368 | VEL-0230 |
VEL-0230 (NC-2300) is a potent, selective cysteine Cathepsins inhibitor with IC50 of 284, 34.5 and 186 nM for Cat B, K and S, respectively.
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DC23860 | Vecabrutinib |
Vecabrutinib (SNS-062) is a potent, reversible, non-covalent BTK inhibitor with IC50 of 2.9 and 4.4 nM for WT BTK and C481S BTK, respectively.
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DC20578 | VDR 4-1 |
VDR 4-1 is a novel non-steroidal, small-molecule agonist of vitamin D receptor (VDR).
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DC11424 | VCMMAE-(PEG)4-DBCO Featured |
VCMMAE-(PEG)4-DBCO is made by MMAE conjugated to DBCO-(PEG)4-vc-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate.
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DC4236 | VCH-916 |
VCH-916 is a novel allosteric inhibitor of HCV NS5B polymerase. The RNA-dependent RNA polymerase (NS5B) of HCV is one of the attractive validated targets for development of new drugs to block HCV infection.
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DC22255 | VB-82252 |
VB-82252 is a highly potent, orally active inhibitor of C. difficile toxins TcdA and TcdB, potently inhibits UDP glucose hydrolysis activity of TcdB (IC50=32 nM).
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