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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease > Phosphodiesterase (PDE)

Phosphodiesterase (PDE)

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Cat. No. Product Name Field of Application Chemical Structure
DC11936 TAK-915
A highly potent, selective, brain-penetrating and orally active phosphodiesterase 2A (PDE2A) inhibitor with IC50 of 0.61 nM.
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DC9581 (S)-(+)-Rolipram
(S)-(+)-Rolipram is a PDE4-inhibitor and an anti-inflammatory agent, less potent than its R enantiomer.
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DC9584 (R)-(-)-Rolipram
(R)-(-)-Rolipram is a potent and cAMP-specific PDE4 inhibitor with IC50 of 0.22 uM; 2.5-fold more potent than (+)-rolipram (IC50= 2.58 uM) in inhibiting membrane-bound PDE 4.
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