4-(2-Boc-aminoethyl)piperidine is a PROTAC linker that can be used in the synthesis of PROTACs.

3'-Methoxy-4'-nitroflavone (MNF) is a specific aryl hydrocarbon receptor (AhR) antagonist. 3'-Methoxy-4'-nitroflavone activates AhR by inhibiting CYP1, the metabolic enzyme of the endogenous ligand FICZ, leading to the accumulation of FICZ. 3'-Methoxy-4'-nitroflavone reverses the anti-apoptotic effect of TCDD, attenuates the activation of Akt and Erk1/2 kinases and the expression of TGFα induced by TCDD. 3'-Methoxy-4'-nitroflavone can be used in research related to breast tumor promotion, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease.

3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP analog. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits the T4 DNA polymerases competitively with dTTP. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits DNA synthesis by T4 wild-type, L98 and CB121 DNA polymerase.

3-Boc-aminomethylazetidine is a PROTAC linker that can be used in the synthesis of PROTACs.

3-(4-Carboxyphenyl)propanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

3-(4-Bromobenzoyl)propionic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

2α-Ferrocenylmethyl-DHT is a dihydrotestosterone-derived ferrocene-steroid conjugate. 2α-Ferrocenylmethyl-DHT inhibits the growth of various cancer cells. 2α-Ferrocenylmethyl-DHT induces S-phase cell cycle arrest in ovarian cancer cells, elevates intracellular iron levels, triggers ROS-dependent cell death, and disrupts the integrity of multicellular tumor spheroids of ovarian cancer cells. 2α-Ferrocenylmethyl-DHT can be used in the research of prostate cancer and ovarian cancer.

2-Tetralone (Beta-Tetralone) is a pro-apoptosis agent. 2-Tetralone targets MDM2 E3 ubiquitin kinase and Bcl-w anti-apoptotic protein and exhibits anticancer activity.

2-Iminopiperidine (compound 13) hydrochloride is an orally active inducible nitric oxide synthase inhibitor. 2-Iminopiperidine (hydrochloride) can be used to investigate NO-mediated arthritis, inflammatory bowel disease, diabetes, allodynia, cerebral ischemia and other central nervous system diseases.

2-Chloro-1,3-propanediol-13C3 is the 13C-labeled 2-Chloro-1,3-propanediol. 2-Chloro-1,3-propanediol is an ester product.

2-Boc-2,6-Diazaspiro[3.3]heptane (hemioxalate) is a PROTAC linker that can be used in the synthesis of PROTACs.

2-(Aminooxy)ethanamine (dihydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.

1-Naphthylacetamide is an orally active nonsteroidal anti-inflammatory agent (NAIA) and also an indole-type auxin plant growth regulator. 1-Naphthylacetamide inhibits inflammatory response-related pathways and modulates plant hormone signaling, exhibiting anti-inflammatory, local anesthetic, antispasmodic, analgesic, and diuretic activities. 1-Naphthylacetamide promotes plant cell expansion, differentiation, and fruit enlargement. Additionally, 1-Naphthylacetamide induces central nervous system (CNS) depression in mice, characterized by reduced spontaneous activity, decreased irritability, decreased muscle tone, and attenuated ear-cuff reflex, ipsilateral flexor reflex, and corneal reflex[1][2].

1-Boc-4-cyanopiperidine is a PROTAC linker that can be used in the synthesis of PROTACs.

1-Boc-4-bromomethylpiperidine is a PROTAC linker that can be used in the synthesis of PROTACs.

13-Hydroxy-alpha-tocopherol is a fat-soluble vitamin E derivative and anticancer agent with antioxidant and antiproliferative activities. 13-Hydroxy-alpha-tocopherol scavenges peroxyl free radicals and protects polyunsaturated fatty acids from oxidative damage. 13-Hydroxy-alpha-tocopherol not only inhibits the growth of glioma cancer cells, but its deficiency is also closely associated with recurrent miscarriage, embryonic growth retardation and death. Clinical observations show that the expression of 13-Hydroxy-alpha-tocopherol is downregulated in the follicular fluid of patients with recurrent miscarriage. 13-Hydroxy-alpha-tocopherol has important application potential in the research of recurrent miscarriage and glioma.

13-cis Acitretin (Isoacitretin; Ro 13-7652) is a retinoid and the major in vivo metabolite of etretinate. 13-cis Acitretin is formed via in vivo isomerization of etretinate. 13-cis Acitretin serves as the primary metabolite in blood.

10-PAHSA-13C4 is the 13C-labeled 10-PAHSA. 10-PAHSA is an endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs).

1,4-Bis(2-bromoethoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs.

1,3-Bis-aminooxy propane dihydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

(S,R,S)-AHPC-Bromooctanoic acid is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC and the corresponding linker. (S,R,S)-AHPC-Bromooctanoic acid can serve as VHL (von Hippel-Lindau) ligand to recruit the VHL protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

(S)-IP-DK143 is a polymeric micellar formulation. (S)-IP-DK143 inhibits the proliferation of cervical cancer cells, induces ROS-mediated apoptosis, and triggers mitochondrial dysfunction. (S)-IP-DK143 activates the p38 MAPK signaling pathway in cervical cancer cells, increases the phosphorylation level of p38, and slightly reduces the phosphorylation level of ERK. (S)-IP-DK143 can be used for the research of cervical cancer.

(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

(S)-5-HT2CR agonist 1 (Compound (S)-16k) is selective 5-HT2CR agonist, with an EC50 of 14 nM. FXa-IN-2 can be used in the research of hyperlocomotion.

(R)-LY-41, R-enantiomer of LY-41, is 2-Sminotetralin derivative and 8-OH-DPAT analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41. (R)-LY-41 can be used for the research of neurological disease, such as depression and anxiety.

(R)-AM-1638 is a R-isomer of AM-1638. AM-1638 is an orally active full agonist of GPR40 (EC50: 0.16 μM).

(R)-5-OH-DPAT ((R)-5-Hydroxy-DPAT) is the R-enantiomer of 5-OH-DPAT. 5-OH-DPAT is a weak antagonist of the dopamine D2 receptor (dopamine D2-receptor). 5-OH-DPAT moderately promotes sexual behavior in male rats.

(7α,24S)-7,24-Dihydroxycholest-4-en-3-one is an oxysterol.

(4-Bromobutoxy)benzene is a PROTAC linker that can be used in the synthesis of PROTACs.

(1R,9R)-rel-Exatecan is a L-Dp derivative. (1R,9R)-rel-Exatecan can be produced by the cleavage of L-Dp (a drug-linker) under cellular conditions.