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Therapeutic Antibodies

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Cat. No. Product Name Field of Application Chemical Structure
A817 Zolbetuximab Biosimilar(Anti-CLDN18.2 Reference Antibody) Featured
Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2. Zolbetuximab mediates specific killing of Claudin-18.2-positive cells through immune effector mechanisms. Zolbetuximab can be used for the research of gastrointestinal adenocarcinomas and pancreatic tumors.
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A816 Academia Sinica patent anti-Clathrin Heavy Chain Biosimilar(Anti-Clathrin Heavy Chain / CHC Reference Antibody) Featured
A815 Brown U. patent anti-CHI3L1 Biosimilar(Anti-CHI3L1 Reference Antibody) Featured
A814 NEO-201 Biosimilar(Anti-CEACAM6 / CD66c Reference Antibody) Featured
A813 Tinurilimab Biosimilar(Anti-CEACAM6 / CD66c Reference Antibody) Featured
Tinurilimab (Bay 1834942) is an anti-CEACAM6 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors.
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A812 Labetuzumab Biosimilar(Anti-CEACAM5 / CEA / CD66e Reference Antibody) Featured
Labetuzumab is a humanised anti-carcinoembryonic antigen (CEA) monoclonal antibody that inhibits tumour growth and sensitises human medullary thyroid cancer xenografts to Dacarbazine chemotherapy.
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A811 Tusamitamab Biosimilar(Anti-CEACAM5 / CEA / CD66e Reference Antibody) Featured
Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative).
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A810 Chaim Sheba Med. Cntr. patent anti-CEACAM1 Biosimilar(Anti-CEACAM1 / CD66a Reference Antibody) Featured
A808 Actoxumab Biosimilar(Anti-Cdiff Toxin A Reference Antibody) Featured
Actoxumab (Anti-C. difficile Toxin A Recombinant Antibody) is a antitoxin antibody against C. difficile toxin A by neutralizing TcdA. Actoxumab prevents both the damage to the gut wall and the inflammatory response, which are associated with C. difficile. Actoxumab has synergy effect with Bezlotoxumab (HY-P9929) targeting TcdB.
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A809 CM-24 Biosimilar(Anti-CEACAM1 / CD66a Reference Antibody) Featured
A807 HKT288 Biosimilar(Anti-CDH6 / K-Cadherin Reference Antibody) Featured
A806 DS-6000A Biosimilar(Anti-CDH6 / K-Cadherin Reference Antibody) Featured
A805 PF-03732010 Biosimilar(Anti-CDH3 / P-cadherin Reference Antibody) Featured
A804 PTA001_A4 Biosimilar(Anti-CDH17 / Cadherin-17 Reference Antibody) Featured
A803 10C12 Biosimilar(Anti-CDH17 / Cadherin-17 Reference Antibody) Featured
A802 RG-6125 Biosimilar(Anti-CDH11 / Cadherin-11 Reference Antibody) Featured
A801 Stem Centrx patent anti-Cadherin-1 Biosimilar(Anti-CDH1 / E-cadherin / CD324 Reference Antibody) Featured
A800 U.California patent anti-CDCP1 Biosimilar(Anti-CDCP1 / CD318 Reference Antibody) Featured
A799 38 E11 Biosimilar(Anti-CDCP1 / CD318 Reference Antibody) Featured
A798 Ign523 Biosimilar(Anti-CD98 Reference Antibody) Featured
A797 DCBY02 Biosimilar(Anti-CD93 Reference Antibody) Featured
A796 Genentech patent anti-CD9 Biosimilar(Anti-CD9 Reference Antibody) Featured
A795 Genentech patent anti-CD83 Biosimilar(Anti-CD83 Reference Antibody) Featured
A794 Polatuzumab Biosimilar(Anti-CD79b Reference Antibody) Featured
Polatuzumab is a monoclonal antibody, which targets CD79b that is found on the surface of B cells. Polatuzumab sticks to the CD79b protein and delivers the chemotherapy compound into the cell. Polatuzumab can be used to synthesize Polatuzumab Vedotin, which is an antibody-drug conjugate (ADC) targeting CD79b .
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A793 Iladatuzumab Biosimilar(Anti-CD79b Reference Antibody) Featured
Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research.
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A792 MilatuzuMab Biosimilar(Anti-CD74 Reference Antibody) Featured
Milatuzumab (hLL1; MEDI-115) is a humanized anti-CD74 monoclonal antibody. CD74, a integral membrane protein, is associated with the promotion of B-cell growth and survival. Milatuzumab causes free radical oxygen generation, and loss of mitochondrial membrane potential. Milatuzumaba also decreases CD20/CD74 aggregates and cell adhesion, to lead to cell death.
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A791 Persongen patent anti-CD7 Biosimilar(Anti-CD7 Reference Antibody) Featured
A790 Grisnilimab Biosimilar(Anti-CD7 Reference Antibody) Featured
Grisnilimab (WT1), a IgG2a monoclonal antibody anti-CD7, is a tumor suppressor involved in the etiology of Wilms' tumor. Grisnilimab regulates the transcription of multiple target genes and may participate in the post-transcriptional processing of RNA.
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A789 Itolizumab Biosimilar(Anti-CD6 Reference Antibody) Featured
Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19.
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A788 Quark patent anti-CD59 Biosimilar(Anti-CD59 Reference Antibody) Featured

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