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2-TEDC

  Cat. No.:  DC72375  
Chemical Structure
132465-10-2
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More than 5000 active chemicals with high quality for research!
Field of application
2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 132465-10-2
Chemical Name: 2-TEDC
SMILES: O=C(OCCC1=CC=CS1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Formula: C16H13NO4S
M.Wt: 315.34
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_36826_DC72375_132465-10-2
COA
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Cat. No. Product name Field of application
DC46158 CAY10698 CAY10698 (compound 1) is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 5.1 μM. CAY10698 is inactive against 5-LOX, 15-LOX-1, 15-LOX-2 and COX-1/2.
DC44939 CDC 5-LO inhibitor Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent and direct inhibitor of 5-LO (5-Lipoxygenase) that reduces 5-LO activity in cell-free assays. CDC also inhibits 12-LO and 15-LO.
DC76861 WY-50295 WY-50295 is an orally active and selective 5-lipoxygenase inhibitor. WY-5029 inhibits LTB4 formation in rat whole blood leukocytes (IC50: 40 μM and oral ED50: 18 mg/kg). WY-50295 can be used in the study of asthma and other leukotriene-dependent diseases.
DC76860 NCTT-956 NCTT-956 is a very effective platelet 12-lipoxygenase (12-LOX) activity-specific inhibitor.
DC76859 BLX-3887 BLX-3887 is a selective 15-lipoxygenase type 1 (15-LO-1) inhibitor with an IC50 of 32 nM. BLX-3887 can be utilized in research related to the 15-LO pathways.
DC76858 15(S)-HEDE 15(S)-HEDE (Compound 8) is an analogue of 15-HEDE-induced acute liver injury and non-alcoholic steatohepatitis (NASH) in mouse models.
DC72894 L 691816 L 691816 is a potent, selective and orally active inhibitors of 5-lipoxygenase. L 691816 can be used for the research of allergies and asthma.
DC72375 2-TEDC 2-TEDC is a potent inhibitor of 5-, 12-, and 15-lipoxygenase with IC50 values of 0.09 μM, 0.013 μM and 0.5 μM, respectively. 2-TEDC can be used for the research of atheroscrelosi.
DC71810 Masoprocol Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes.
DC71055 HZ52 HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes.
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