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Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > Estrogen Receptor/ERR

(E/Z)-4-hydroxy Tamoxifen

  Cat. No.:  DC10832   Featured
Chemical Structure
68392-35-8
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More than 5000 active chemicals with high quality for research!
Field of application
(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen that is formed by the action of cytochrome P450 2D6 in human liver.
Chemicals PropertiesBiological activity COAMSDSRelated productsDatasheet
Cas No.: 68392-35-8
Chemical Name: Afimoxifene
Synonyms: Afimoxifene;4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;4-Hydroxytamoxifen;(E,Z)-4-hydroxytamoxifen;1-[4-(2-Diaethylamino-aethoxy)-phenyl]-propan-1-on,Hydrochlorid;1-[4-(2-diethylamino-ethoxy)-phenyl]-propan-1-one,hydrochloride;1-[4-(2-diethylaminoethyloxy)phenyl]propan-1-one hydrochloride;1-[4-(2-dimethylaminoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbut-1-ene;4-hydroxytamoxifene;Propiophenone,4'-[2-(diethylamino)ethoxy]-,hydrochloride;4-OHT;cis;trans-4-Hydroxytamoxifen;(E/Z)-4-Hydroxy Tamoxifen;(E/Z)-4-Hydroxytamoxifen
SMILES: CN(CCOC1C=CC(/C(=C(/C2C=CC=CC=2)\CC)/C2C=CC(O)=CC=2)=CC=1)C
Formula: C26H29NO2
M.Wt: 387.51396
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: (E/Z)-4-Hydroxytamoxifen is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is an estrogen receptor modulator.
COA
MSDS
Cat. No. Product name Field of application
DC10755 LSZ-102 LSZ102 is a potent, orally bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
DC8265 Endoxifen Endoxifen is a Estrogen receptor α (ERα) ligand; potent antiestrogen,an active metabolite of the cancer drug tamoxifen.
DC9268 AZD9496 AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator(Ki=0.7 nM) and antagonist.
DC10832 (E/Z)-4-hydroxy Tamoxifen (E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen that is formed by the action of cytochrome P450 2D6 in human liver.
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