Cat. No.:  DC39817   Featured
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
LDC203974(IMT1B) is a highly specific inhibitor of human mitochondrial RNA polymerase (POLRMT) with improved pharmacokinetic profiles than LDC195943(IMT1).
Cas No.: 2304621-06-3
Chemical Name: 3-​Piperidinecarboxylic acid, 1-​[(2R)​-​2-​[[4-​(2-​chloro-​4-​fluorophenyl)​-​2-​oxo-​2H-​1-​benzopyran-​7-​yl]​oxy]​-​1-​oxopropyl]​-​, (3S)​-
Synonyms: LDC203974;LDC 203974;LDC-203974;IMT1B,IMT1-B IMT1 B
SMILES: C1(C(Cl)=CC(F)=CC=1)C1=CC(=O)OC2=C1C=CC(=C2)O[C@@H](C(=O)N1CCC[C@H](C(=O)O)C1)C
Formula: C24H21ClFNO6
M.Wt: 473.88
Purity: >99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: Small-molecule inhibitors of human mitochondrial DNA transcription-Nature,Published: 16 December 2020
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Cat. No. Product name Field of application
DC52050 Lats-IN-1(TRULI ) Lats-IN-1 is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. Lats-IN-1 promotes Yap-dependent proliferation in postmitotic mammalian tissues.
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DC51011 IXA6 IXA6 is a novel small molecule compound of inducing IRE1 RNase activity.
DC51005 BMS986313 BMS-986313 is a tricyclic-carbocyclic RORγt inverse agonist and shows potent GaL4-Luc reporter(GAL4) and human whole blood (hWB) activity (EC50s of 3.6 nM and 50 nM, respectively.
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DC51000 Sisunatovir (Synonyms: RV521) Sisunatovir (RV521), an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC50s of 1.4 nM and 1.0 nM, respectively.