TRPC6 activator compound 2|CAS |DC Dcchemicals

Cas No.:	931591-94-5
Formula:	C₁₉H₂₁F₂N₃O
M.Wt:	345.39
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	Discovery of a novel piperazine derivative, cmp2: a selective TRPC6 activator suitable for treatment of synaptic deficiency in Alzheimer’s disease hippocampal neurons-Sci Rep. 2024 Oct 9;14:23512. doi: 10.1038/s41598-024-73849-z

Description:	TRPC6 activator compound 2 is selective activator of TRPC6 that does not potentiate TRPC3 and mTRPC7. Comp2 is able to cross BBB.
References:	Discovery of a novel piperazine derivative, cmp2: a selective TRPC6 activator suitable for treatment of synaptic deficiency in Alzheimer’s disease hippocampal neurons-Sci Rep. 2024 Oct 9;14:23512. doi: 10.1038/s41598-024-73849-z

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